● Why Conditional Knockout (cKO) Mice are Used in Research
● How to Develop Conditional Knockout Models
● Successful Case Study on Conditional Knockout Mice Research
● Conditional Knockout Mice Capabilities
● Resources for Conditional Knockout Model Development
Scientific Handbook:
Advancing Your Research with
Conditional Knockout Mice
Conditional Knockout Mice
The conditional knockout (cKO) mouse model is a powerful tool for investigating disease mechanisms and is specifically used to study specific gene functions among related human disease pathologies. While traditional knockout (KO) mice have a gene disabled throughout the organism, conditional knockout mice may be obtained with a gene deleted only in specific tissues or on an inducible basis. Compared with constitutively expressed gene mutations, conditional models provide greater temporal and regional control of gene expression – often serving as a more accurate model for studying human diseases.
Herein, Cyagen’s experts have put together a Scientific Handbook on how conditional knockout mice can be used to advance your research.
Outline of Contents:
About Cyagen
With more than 15 years’ experience in genetic engineering, Cyagen offers a complete range of model generation services, including: custom genetically engineered models, ready-to-use catalog models, drug development models, colony management, and phenotype analysis - enabling researchers worldwide to create, manage, and monitor models with ease.
In addition to animal model generation, Cyagen has established a range of supporting services, such as animal breeding, embryo/sperm cryopreservation, histology, and transcriptome profiling. Outsourcing these services to Cyagen is a more cost-effective way of conducting your research. All these services are performed by experienced specialists following standardized procedures, so we can guarantee delivery of high-quality services and data acquisition with unbeatable price and turnaround.
Contact us with your model(s) of interest and our experts will be in touch with you.
