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Cyagen's Lucky Draw
Cyagen Catalog Knockout Models
Description

Celebrate Black Friday all November long by entering Cyagen's Catalog Lucky Draw for Knockout Catalog Models. Established in 2020, the Cyagen Knockout Catalog Models repository provides ready-to-use gene knockout (KO) mice with rapid turnaround and competitive prices.

There are limited quantities of our top prizes available – including free breeding ($2,500 value) or up to $2,000 credit – enter before they disappear!

CYAGEN BLACK FRIDAY LUCKY DRAW
Terms and Conditions

Promotion Period: Apply for a Lucky Draw voucher before Dec. 1, 2020 .

December 1, 2020 Update: As the popularity of Lucky Draw Event, we have extended the promotion deadline to December 31, 2020

Lucky Draw Voucher Details: Vouchers are valid for use until December 31, 2020. Non-refundable, non-transferable, and valid for a single transaction only. It has no cash value and cannot be exchanged for cash. Not valid in conjunction with other special promotions. Other discounts cannot be applied while using any voucher.

Eligibility: Academic customers in the United States, European Union, and United Kingdom. Each participating customer is limited to one (1) entry. Contact us at animal-service@cyagen.com for eligibility in other regions or for commercial use.

Advantages of catalog models
Reliable:

No risk of failure: Our catalog features gene knockout mice that have been strictly analyzed to ensure 100% positive knockout.

Professional Technical Support

AAALAC-Accredited and OLAW Assured

Efficient:

Deliverables: as fast as 3 month

Reduced paperwork: Inquire online to place an order, one click to get detailed information and modeling guidance, backed by a powerful database.

Economical:

100% pure B6 background eliminates need for backcrossing – most repositories have mixed backgrounds

Inexpensive: Cost of catalog lines cannot be beaten by any model generation approach

Applications for KO Mice

Target discovery and target confirmation

Data from in vitro experiments are not reliable enough on their own; in vivo data is required to validate the target for a successful drug development program. KO mice mimic the activity of 100% effective antagonists. Use our available lines as tools for fast evaluation of your target.

In vivo compound specificity

Non-specific drugs may cause dangerous off-target effects, which are the primary cause of drug failures. Evaluating drug activity on similar targets (same family) or non-related targets can significantly de-risk a promising compound. KO models can remove a functional protein target, providing an in vivo system to detect potential off-target effects of an antagonist.

Clinical studies

Investigate physiological responses that may occur in patients during clinical trials, deepen your understanding of the physiological role of your target, and provide rapid answer to agencies' questions about the in vivo pathology related to your target.