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Custom Models
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- ● Diet-Induced Obesity (DIO) Mouse Model
- ● Type 1 Diabetes Mellitus (T1DM) Mouse Model
- ● Type 2 Diabetes Mellitus (T2DM) Mouse Model
- ● Diet-induced Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) Mouse Model
- ● Chemically Induced Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) Mouse Model
- ● Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) Mouse Model (Gene-editing)
- ● Composite (Combined) Model - Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) Model
- ● Composite Model - Atherosclerosis Mouse Model
- ● Atherosclerosis Mouse Model (Gene-editing)
- ● Acute Pancreatitis Mouse Model
- ● Chronic Pancreatitis Mouse Model
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Testimonials
"I've been very happy with Cyagen's service so I've been referring a lot of colleagues... thanks for
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Citations
IMMUNITY 47:107 (2017) IF=22.845
You may also be interested in
Item Number: C001344
Background: C57BL/6JCya
Genotype: Homozygous
Mouse Status: Homozygous knockout mice are developmentally normal and fertile
In this mouse homozygote, the J-segment of the Ig heavy chain locus is completely deleted, resulting in the inability of the cell to produce a recombinant version of the complete heavy chain variable region. The B cells of Ighj knockout (KO) mice have undergone dramatic changes in developmental process and cell number, which can be used as an animal model of B cell immune deficiency. Ighj KO mice retain other immune cells except B cells, so changes in other immune cells can be detected in Ighj KO mice.
Immunology;
Inflammation; Autoimmunity Research.
• Detection of B cells
Figure 1. Detection of B cells in peripheral blood and spleen of Ighj KO homozygous mice
The results showed that B cell deletion was detected in the peripheral blood and spleen of Ighj KO homozygous mice.
Cyagen can provide you with a variety of drug evaluation models along with phenotype analysis services – delivering reliable and expedient data reporting for your project.
Inquiries and Quote Requests
Request a quote now. Alternatively, you can always email animal-service@cyagen.com or call 800-921-8930 to inquire about our services or obtain a quote for your project.
About Cyagen
● 15+ years' experience in custom animal model generation
● 78,000+ animal models generated and delivered worldwide
● 6,200+ citations in SCI journals
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