Custom Models
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- ● Diet-Induced Obesity (DIO) Mouse Model
- ● Type 1 Diabetes Mellitus (T1DM) Mouse Model
- ● Type 2 Diabetes Mellitus (T2DM) Mouse Model
- ● Diet-induced Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) Mouse Model
- ● Chemically Induced Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) Mouse Model
- ● Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) Mouse Model (Gene-editing)
- ● Composite (Combined) Model - Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) Model
- ● Composite Model - Atherosclerosis Mouse Model
- ● Atherosclerosis Mouse Model (Gene-editing)
- ● Acute Pancreatitis Mouse Model
- ● Chronic Pancreatitis Mouse Model
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Citations
IMMUNITY 47:107 (2017) IF=22.845
Reln-P2A-iCre Mice
Catalog Number: C001671
Strain Name: C57BL/6JCya-Relnem1(P2A-iCre)/Cya
Genetic Background: C57BL/6JCya
Examples of Expressing Tissues/Cells: Cerebral cortex, hippocampus, cerebellum, and Reln-positive cells
Strain Description
The TGA stop codon was replaced with the "P2A-iCre" cassette. Cre recombinase is expressed under the regulatory control of Reln gene elements, without impacting the endogenous expression of the Reln gene.
Announcement
The insertion site of the Cre recombinase gene expression cassette in this strain is located on chromosome 5. Please avoid breeding with gene-edited mice targeting genes on the same chromosome as the Cre mouse when conducting mating.
