Catalog Number: I001158
Strain Name: C57BL/6JCya-Tac1em1(IRES-iCre)/Cya
Genetic Background: C57BL/6JCya
Examples of Expressing Tissues/Cells: para olfactory bulb, anterior olfactory nucleus, thalamus, VMH, and midbrain structures (e.g., superior colliculus), as well as in decentralized cells in the caudate, septum, hypothalamus, midbrain, hindbrain, and cerebellum.
Strain Description
The "IRES-iCre" cassette was inserted ~10 bp downstream of the TAA stop codon. Cre recombinase is expressed under the regulatory control of Tac1 gene elements, without impacting the endogenous expression of the Tac1 gene.
Announcement
The insertion site of the Cre recombinase gene expression cassette in this strain is located on chromosome 6. Please avoid breeding with gene-edited mice targeting genes on the same chromosome as the Cre mouse when conducting mating.