Most Popular
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Research Trend
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| Fight for Sight - Targeting Genetic Factors of Ophthalmic Diseases |
| Apr 22, 2022 |
| Genes play a highly significant role in the pathogenesis of eye diseases, some of which are highly prevalent in children and adults. Read More > |
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Research Trend
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| How Can Lentiviral Vectors Help CGT Research? |
| Apr 19, 2022 |
| Lentiviruses (LVs) are one of the commonly used delivery vectors for cell and gene therapy, which have been successfully applied to the preparation of CAR-T cells. Read More > |
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Research Trend
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| Announcing the Release of Rare Disease Data Center (RDDC) |
| Mar 04, 2022 |
| In February 2022, the Rare Disease Data Center (RDDC) was officially released to the international research community. Read More > |
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Research Trend
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| Induced Pluripotent Stem (iPS) Cells & Gene Editing |
| Feb 24, 2022 |
| In recent years, the application of CRISPR-mediated gene editing in iPS cells has attracted more and more attention. Read More > |
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Research Trend
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| Inducible Humanized ACE2 Mouse Model For Coronavirus (COVID-19) Research |
| Feb 15, 2022 |
| The newly-developed K18 promoter-driven hACE2-Cre-ERT2 knock-in (hACE2 KI) mouse model with a C57BL/6J background provides an additional platform for continued research. Read More > |
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Research Trend
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| Analyzing the Process of CAR T-Cell Therapy Research |
| Feb 10, 2022 |
| This article focuses on the process of developing CAR T-cell therapy and discusses the importance of each preclinical and clinical stage in the research of CAR T-cell therapy. Read More > |
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Research Trend
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| Application of AAV-mediated Gene Therapy in Metabolic Disorders |
| Jan 24, 2022 |
| The application of recombinant Adeno-Associated Virus (rAAV) drugs in clinical trials of metabolic diseases around the world is mainly concentrated among the following indications Read More > |
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Research Trend
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| Application of Gene Therapy in Mucopolysaccharidosis IVA (MPS IVA) (Part B) |
| Jan 20, 2022 |
| In Part A, we describe how the Mucopolysaccharidosis IVA (MPS IVA, MPSIVA) rat model is generated. Please see Part B which we explore other promising applications of AAV9-Galns treatments. Read More > |
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Research Trend
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| The Ultimate Guide to Humanized Mice for Antibody Research |
| Jan 13, 2022 |
| With the development of research on the impact of immunity and inflammation on cancer, the performance of humanized mice attract tremendous attention in cancer clinical research. Read More > |
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Research Trend
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| Application of Gene Therapy in Mucopolysaccharidosis IVA (MPS IVA) (Part A) |
| Jan 12, 2022 |
| Mucopolysaccharidosis IVA (MPS IVA) - also known as Morquio Syndrome, type A - is inherited in an autosomal recessive manner and caused by mutations in the GALNS gene. Read More > |
