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World Hemophilia Day | China Approves First AAV Gene Therapy Drug: How Humanized Animal Models Enable Breakthroughs in Rare Disease Treatment
Apr 17, 2025
On April 10, China’s National Medical Products Administration (NMPA) officially approved Dalnacogene Pankparvovec Injection (brand name: XinJiuning, research code: BBM-H901) Read More >
Research Trends
Preliminary Data: Inducible PKD Mouse Model Shows Phenotype in as Fast as 3 Weeks
Apr 11, 2025
ADPKD is the most common inherited kidney disorder worldwide and a major cause of end-stage kidney disease (ESKD). Read More >
Research Trends
HUGO Series Humanized Mice: Revolutionizing Antibody Discovery and Gene Therapy Research
Apr 03, 2025
An exclusive interview with Dr. Yingbin (Marvin) Ouyang, Executive Vice President and Chief Scientific Officer at Cyagen, on breakthrough advancements in humanized genomic ortholog mouse models. Read More >
Research Trends
NLRP3 Inflammasome: A Rising Star in Broad-Spectrum Anti-inflammatory Drug Discovery
Mar 28, 2025
In April 2024, Cell published a landmark review article titled “From Periphery to Center Stage: 50 Years of Advancements in Innate Immunity” to mark its 50th anniversary. Read More >
Research Trends
Next-Generation Fluorescent Reporter Mice: Advanced Tools for Optogenetics and Cellular Fate Mapping
Mar 21, 2025
Since the discovery of green fluorescent protein (GFP), fluorescent labeling technology has rapidly transformed the landscape of genetic research. Read More >
Research Trends
From the 'Illusion of Happiness' to the Reality of Angelman Syndrome: Ube3a KO Mice Expose the Hidden Tragedy
Mar 13, 2025
Children with Angelman Syndrome (AS) are often described as "smiling angels" due to their frequent laughter and joyful expressions. Read More >
Research Trends
Revolutionizing Duchenne Muscular Dystrophy Research: Humanized Mouse Models Pave the Way
Mar 07, 2025
Imagine a world where children with Duchenne Muscular Dystrophy (DMD) can run, play, and live without the looming threat of muscle degeneration. Read More >
Research Trends
Empowering Rare Metabolic Disorder Research: Gcdh Knockout Mouse Model of Glutaric Acidemia
Feb 28, 2025
Glutaric Acidemia Type 1 (GA1), also called Glutaric Aciduria Type 1, is a rare autosomal recessive metabolic disorder. It is caused by changes in the Gcdh gene. Read More >
Research Trends
Discover the FVB-Abcb4 Knockout Mouse Model: Advancing Intrahepatic Cholestasis Research
Feb 21, 2025
Progressive familial intrahepatic cholestasis type 3 (PFIC3) is a severe genetic liver disorder that leads to progressive liver damage and often necessitates liver transplantation. Read More >
Research Trends
XDH Humanized Mouse Model for Hyperuricemia and Gout Drug Research
Feb 14, 2025
Hyperuricemia, a metabolic disorder characterized by elevated uric acid levels in the blood, is a growing global health concern. Read More >