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Weekly Gene
【Gene of the Week】DMD: Duchenne Muscular Dystrophy Pathogenic Gene
Jul 02, 2021
Duchenne muscular dystrophy (DMD) is a genetic disorder characterized by progressive muscle degeneration. It usually starts in early childhood. Read More >
Weekly Gene
Pathogenic Gene of Neurodevelopmental Disorders - MECP2 Gene
May 27, 2021
Neurodevelopmental disorders are impairments of the brain and central nervous system that affect a patient’s behavior and cognition. In this article we review the MECP2 gene, a pathogenic gene of neurodevelopmental disorders, hoping to help researchers gaining proper understanding of the gene, its encoded MeCP2 protein, and related neurodevelopmental disorders. Read More >
Weekly Gene
LRRK2: A Pathogenic Gene of Parkinson's Disease (PD)
Apr 23, 2021
Parkinson's Disease (PD) is a neurodegenerative disease that cannot be cured. In this article, we review the background information, research insights and applications on LRRK2, a pathogenic gene of PD, providing useful information for further scientific innovation. Read More >
Weekly Gene
PRKN: A Pathogenic Gene of Parkinson's Disease (PD)
Apr 22, 2021
Parkinson's disease (PD) is a neurodegenerative disorder that affects behavior and motor skills. In this article, we review the background information, research insights, and applications related to PRKN, a pathogenic gene of PD. Read More >
Weekly Gene
TARDBP: A Pathogenic Gene of Neurodegenerative Diseases
Apr 15, 2021
Neurodegenerative diseases have a multitude of factors contributing to their pathogenesis. In the first of our Weekly Gene features covering pathogenic genes of neurodegenerative diseases, we review the functionality of TARDBP. This review, as well as the upcoming Weekly Gene articles, aim to help researchers explore potential therapeutics for neurogenerative diseases. Read More >
Weekly Gene
SNCA: A Pathogenic Gene of Neurodegenerative Diseases
Apr 15, 2021
It is well known that genes play a major role in the pathogenesis of neurodegenerative diseases. There have been major efforts in biomedical research to learn about disease-related genes, which has led to highly targeted therapeutics for several diseases that were previously untreatable. Read More >
Weekly Gene
The Pathogenic Gene of Huntington's disease – HTT
Mar 24, 2021
Huntington's disease (HD) is a rare, progressive brain disorder that is inherited in an autosomal dominant manner - this disorder is caused by a defective huntingtin (HTT) protein that changes the brain, causing patients to experience problems with behavior, thinking and involuntary movements. Read More >
Weekly Gene
Immunology and Inflammation Research - IL17A
Mar 17, 2021
Since IL17A plays an important role in infectious diseases, inflammatory, autoimmune diseases and cancer studies, IL17A has become a hot research target for many studies. In this Gene of the Week article, we have collected some insights on IL17A research progress and development trends, aiming to inspire even more scientific innovations. Read More >
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Weekly Gene
Pathogenic Genes of Rare Disease - SMN1 in Spinal Muscular Atrophy Research
Mar 05, 2021
cord, which affects the central nervous system, peripheral nervous system, and voluntary muscle movement. The primary pathogenic gene of spinal muscular atrophy is the survival of motor neuron 1 (SMN1) gene, mutations of which cause a deficiency of SMN motor neuron protein – ultimately resulting in Chromosome 5 SMA, the most common form of SMA. Read More >
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Weekly Gene
【Gene of the Week】Metabolism & Cardiovascular Diseases - SIRT3
Feb 26, 2021
The SIRT3 gene plays an important role in the pathogenesis of metabolic, cardiovascular, and neurodegenerative diseases. In this article, we review the functionality of SIRT3 and explore its role in metabolism & cardiovascular disease studies - bringing together insights to SIRT3 gene research developments to provide inspiration for your scientific innovation. Read More >