Most Popular
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Research Trend
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| Improving Cancer Models with Humanized Mice |
| Jul 09, 2019 |
| Mouse models have been instrumental in elucidating the pathobiology of cancer formation and inhibition, including that of Colorectal Cancers (CRC) and Prostate Cancers. Read More > |
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Newsletter
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| Custom Animal Models for Improving Human Disease Research |
| Jun 24, 2019 |
| If your lab is working on research projects that utilize mouse/rat models, off-the-shelf models often come with limitations that may be addressed through genomic modifications to improve homology. Read More > |
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Research Trend
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| Application of Toll-Like Receptors (TLRs) Animal Models in Cancer and Autoimmune Disorders |
| Jun 17, 2019 |
| Toll-like receptors (TLRs) are a class of transmembrane proteins that play essential roles in mammalian innate immune responses against infection. In general, TLRs can recognize structurally conserved molecules, collectively referred to Read More > |
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Research Trend
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| Custom Animal Models of Neurodegeneration for Investigation of Potential Therapeutics |
| Jun 12, 2019 |
| Neurodegenerative diseases have a multitude of factors contributing to their pathogenesis, such as tau accumulation, amyloid-β deposition, and altered network oscillations. Synaptic and neuronal loss are also typical of many of neurodegenerative diseases Read More > |
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Research Trend
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| How microRNA may be used to promote heart regeneration |
| Jun 05, 2019 |
| Recent research has aimed to enhance the regeneration capacity of adult cardiomyocytes (CMs), in part by addressing their withdrawal from the cell cycle following myocardial infarction (MI). As a suggested regulator of endogenous CM proliferation Read More > |
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Research Trend
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| Treatment and Male-Bias in Autistic Mice |
| Jan 22, 2018 |
| Although humans and mice are separated by 100 million years of evolution, mouse and rat models have continually proven themselves as extremely powerful research tools. Many mouse and rat genetic models can even recapitulate complex and... Read More > |
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Latest Discovery
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| Metastasis triggered by macrophage cytoplasm |
| Dec 11, 2017 |
| Macrophages are the first line of defense against infections, playing important roles in consuming pathogens and in regulating inflammation. In general, these functions help maintain a healthy organism, keeping infections at bay and promoting... Read More > |
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Latest Discovery
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| Anorexic mice |
| Nov 20, 2017 |
| During the past several years, there has been an increasing public awareness of mental illness and their societal and health consequences. Eating disorders represent one of the most damaging groups of mental illnesses. Current estimates are... Read More > |
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Latest Discovery
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| 'Trimming the fat' with CRISPR |
| Oct 31, 2017 |
| Around 20 million years ago, for unknown reasons, wild pigs lost an important metabolic gene known as uncoupling protein 1 (UCP1). In most mammals this gene plays a major role in generating body heat for thermoregulation by burning fat... Read More > |
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Latest Discovery
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| A mammalian half-day clock |
| Oct 20, 2017 |
| Last month, the Nobel Foundation recognized Jeffrey Hall, Michael Rosbash, and Michael Young "for their discoveries of molecular mechanisms controlling the circadian rhythm". This 24-hour "clock" influences many physiological processes... Read More > |
