Most Popular
Weekly Gene
[Gene of the Week] The Next Generation Target for Immunotherapy - CD134 (TNFRSF4)
Feb 18, 2021
Immune checkpoint proteins (ICP) are a group of signaling molecules possessed by immune cells that can regulate and control the persistence of immune response. The immune checkpoint signaling pathway consists of inhibitory and stimulatory pathways that maintain self-tolerance and assist with the immune response. Read More >
Newsletter
Weekly Gene
[Gene of the Week] Alzheimer's Disease and Genes - APOE (Apolipoprotein E)
Dec 22, 2020
In our fourth Gene of the Week article, we continue covering genes related to the development of Alzheimer's disease (AD). Several mutations in APOE (Apolipoprotein E) have been identified to not only increase the risk of developing AD, but other neurological and cardiovascular diseases. Read More >
Newsletter
Weekly Gene
[Gene of the Week] Alzheimer's Disease and Genes - TREM2
Dec 14, 2020
Specific mutations in TREM2 (Triggering Receptor Expressed on Myeloid Cells 2) have been confirmed to increase the risk of developing late-onset AD. Here, we review the current data detailing the function of TREM2 and its role in Alzheimer's disease (AD). Read More >
Weekly Gene
Research Trend
[Gene of the Week] Alzheimer's Disease and Genes - PSEN1 (Presenilin 1)
Nov 12, 2020
Alzheimer's disease (AD) is the most common age-related neurodegenerative disorder, which affects 20 to 30 million individuals worldwide. Currently, no effective therapies to treat or cure this disease have been developed. In this review, we discuss the current research and understanding of the PSEN1 gene and its mutation which causes familial Alzheimer's disease (FAD). Read More >
Research Trend
Weekly Gene
[Gene of the Week] Alzheimer's Disease and Genes - APP (Amyloid Precursor Protein)
Oct 21, 2020
It is well known that genes play a major role in many human diseases - for this reason they are an important research topic in the field of life science and medicine. How can the public quickly grasp the recent research on disease-related genes, when the only resources out about them are long complex academic journals? Read More >