Most Popular
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Research Trends
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| Taking a Closer Look at Common Animal Models for Tumor Diseases: Colorectal Cancer |
| Sep 28, 2023 |
| Colorectal cancer is a common malignancy that occurs in the colon, a part of the digestive tract. It is typically found at the junction of the rectum and sigmoid colon and has the highest incidence in the 40 to 50-year-old age group. Read More > |
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Research Trends
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| Rare Diseases Are Not Rare: The Mechanistic Research on Kennedy Disease (KD) |
| Sep 22, 2023 |
| Kennedy disease (KD), also known as Spinal and Bulbar Muscular Atrophy (SBMA), is a recessive, X-linked, adult-onset motor neuron disease characterized by the slow, progressive weakness of the bulbar and limb muscles. Kennedy disease predominantly affects adult males, with an estimated global incidence of 1-2/100,000. Read More > |
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Research Trends
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| Do not give up chasing the light—Gene therapy aids the blind in regaining their sight |
| Sep 19, 2023 |
| It is said that the eyes are the windows to the soul, but there are many people with congenital blindness who cannot "see" the light. According to publicly available data from the World Health Organization, there are at least 2.2 billion people globally with impaired vision or blindness. Read More > |
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Research Trends
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| Exploring the Power of the Cre-Lox System: Conditional Gene Targeting in Mice for In Vivo Applications |
| Sep 08, 2023 |
| Conditional gene targeting in mice has revolutionized the field of molecular biology and genetic engineering. In vivo applications of the Cre-lox system are highly efficient, specific, and versatile. The Cre-lox system is a powerful tool to manipulate and study gene function in vivo, and it relies on the Cre recombinase enzyme to induce site-specific recombination between two LoxP sites. Read More > |
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Research Trends
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| What is Familial Exudative Vitreoretinopathy (FEVR)? What are the mouse models for it? |
| Aug 31, 2023 |
| Familial Exudative Vitreoretinopathy (FEVR) is a group of rare hereditary retinal disorders characterized by abnormal retinal vascular development, leading to incomplete peripheral retinal vascularization and subsequent retinal ischemia. Read More > |
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Research Trends
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| Can Childhood Metabolic Disorders Actually Lead to Heart Failure? Gene Therapy Research Provides Hope |
| Aug 18, 2023 |
| Have you ever encountered patients who, despite growing normally during early childhood, gradually begin to exhibit symptoms such as facial abnormalities, growth retardation, delayed intellectual development, skeletal deformities, neurological abnormalities, and cardiac involvement? Read More > |
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Research Trends
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| Recommended Classic Mouse Models for Metabolic and Cardiovascular Diseases! Double Assurance with Validation Data and Efficacy Evaluation System |
| Aug 11, 2023 |
| Cardiovascular diseases are now the leading cause of death worldwide, posing a significant threat to human health. In China alone, there are approximately 330 million people with cardiovascular disease and 450 million with metabolic disease. Read More > |
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Research Trends
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| What are the Best Transgenic Animal Models for Alzheimer's Disease Research? |
| Jun 20, 2023 |
| When it comes to Alzheimer's disease (AD), people may think of various emotional scenes portrayed in movies and TV shows. However, the reality is much more cruel, as we can see from the trending topic“They Will Forget Love And They Will Forget You”. Read More > |
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Research Trends
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| Common Mouse Models for Preclinical Alzheimer's Disease Research |
| Jun 15, 2023 |
| After being diagnosed with Alzheimer’s in his later years, the famous British fantasy author Terry Pratchett described the disease in his writings: “On the first day of my journalistic career I saw my first corpse… All I can say is that, compared with his horrific demise, Alzheimer's is a walk in the park. Except with Alzheimer's my park keeps changing. The trees get up and walk over there, the benches go missing and the paths seem to be unwinding into particularly vindictive serpents.”. Read More > |
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Research Trends
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| How to overcome the challenge of model selection in DMD gene therapy? |
| May 30, 2023 |
| Duchenne muscular dystrophy (DMD) is an X-linked recessive genetic disorder caused by mutations in the DMD gene, resulting in abnormal function of the dystrophin protein. Read More > |
