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Research Trend
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| Application of Toll-Like Receptors (TLRs) Animal Models in Cancer and Autoimmune Disorders |
| Jun 17, 2019 |
| Toll-like receptors (TLRs) are a class of transmembrane proteins that play essential roles in mammalian innate immune responses against infection. In general, TLRs can recognize structurally conserved molecules, collectively referred to Read More > |
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| Custom Animal Models of Neurodegeneration for Investigation of Potential Therapeutics |
| Jun 12, 2019 |
| Neurodegenerative diseases have a multitude of factors contributing to their pathogenesis, such as tau accumulation, amyloid-β deposition, and altered network oscillations. Synaptic and neuronal loss are also typical of many of neurodegenerative diseases Read More > |
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| How microRNA may be used to promote heart regeneration |
| Jun 05, 2019 |
| Recent research has aimed to enhance the regeneration capacity of adult cardiomyocytes (CMs), in part by addressing their withdrawal from the cell cycle following myocardial infarction (MI). As a suggested regulator of endogenous CM proliferation Read More > |
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Research Trend
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| Treatment and Male-Bias in Autistic Mice |
| Jan 22, 2018 |
| Although humans and mice are separated by 100 million years of evolution, mouse and rat models have continually proven themselves as extremely powerful research tools. Many mouse and rat genetic models can even recapitulate complex and... Read More > |
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Research Trend
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| Controlling when and where: Conditional and inducible gene expression |
| Jul 26, 2017 |
| In the early days of engineered animal models, simple knockout and transgenic mice were used to examine gene function. Researchers began to dissect the roles of individual genes by studying phenotypes of mice lacking or... Read More > |
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Research Trend
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| Optogenetics: Light-control of genes, pathways, and cells |
| Jul 12, 2017 |
| Optogenenetics refers to a family of techniques which allow modulation of biological processes using light. Over the past 12 years, optogenetics has... Read More > |
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Research Trend
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| Making mice live longer, then humans |
| Jun 28, 2017 |
| Invariably, everyone gets old. However, as a true testament to human stubbornness, research toward a “cure” for aging has never stopped. Over the past... Read More > |
