Most Popular
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Research Trends
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| Y Maze Behavioral Task: Studying the function of spatial learning and memory in Neuroscience research |
| Dec 29, 2022 |
| Since animals can't speak, they can't tell you whether they remember what just happened, or what they are experiencing at this moment. The most direct way to understand what they are thinking is to observe their behaviors. Read More > |
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Research Trends
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| A Good Helper for SARS-CoV-2 & COVID-19 Research: Selection and Application of Mouse Models |
| Dec 06, 2022 |
| Animal models have assisted researchers' understanding of COVID-19 pathogenesis and host immune response to SARS-CoV-2 infection, and are of great significance in helping the rapid development of disease preventatives, vaccines, and treatments. Read More > |
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Research Trends
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| Application of Flow Cytometry in Preclinical CAR-T Development |
| Nov 28, 2022 |
| Chimeric Antigen Receptor T-Cell (CAR-T) Immunotherapy uses genetic engineering technology to transform autologous or allogeneic T cells into new killer cells targeting tumor-specific antigens, by which remarkable results have been achieved in the treatment of hematological malignancies. Read More > |
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Research Trends
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| Animal Welfare Focus: Humane Endpoints in Rats and Mice in Tumor Research Programs |
| Nov 04, 2022 |
| In recent years, more and more people advocate the "3Rs" principle of experimental animals: Reduction, Replacement, and Refinement. Read More > |
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Research Trends
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| Vision Stolen by Years - Age-related Macular Degeneration |
| Oct 26, 2022 |
| Many older adults experience a noticeable loss of vision as age increases, but the inability to see fine details in the center of vision may be a sign of age-related macular degeneration (AMD). Read More > |
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Research Trends
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| Accelerating CAR-T Cell Therapy Research |
| Oct 13, 2022 |
| By using the body's own immune system to kill tumor cells, immune cell therapy is anticipated to be a breakthrough strategy to "cure" many types of cancer. Among them, chimeric antigen receptor T-cell immunotherapy (CAR-T) has achieved remarkable results in the treatment of various hematological malignancies. As of 2022, seven CAR-T cell therapy products have been launched globally, including three in China. Read More > |
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Research Trends
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| Research Progress of CAR-T Therapy in Solid Tumor Treatment |
| Sep 23, 2022 |
| CAR-T cell therapy research has developed rapidly in recent years, largely based on the remarkable efficacy of CAR-T therapy in hematological malignancies, and scientists are moving quickly to apply this innovative immunotherapy to the treatment of solid tumors, including sarcomas, carcinomas, and lymphomas. Herein, we review the background of CAR-T cell therapy in solid tumor treatment, common research targets, CAR-T optimization strategy, and clinical research progress. Read More > |
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Research Trends
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| A Study on The Mechanism of Achromatopsia |
| Sep 15, 2022 |
| Patients with achromatopsia (ACHM) have abnormal color discrimination on the three color vision axes corresponding to the three cone cells. The patient's three cones, which sense red, green and blue, are completely inoperative, so they cannot distinguish between different colors. Read More > |
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Research Trends
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| CRISPR-Pro-Mediated Gene Editing System for Effective Treatment of X-linked Retinitis Pigmentosa |
| Aug 09, 2022 |
| Mutations in the retinitis pigmentosa GTPase regulator (RPGR) gene are associated with X-linked retinitis pigmentosa (XLRP), which accounts for 10% to 20% of all cases of retinitis pigmentosa (RP) and is one of its most severe forms. Herein, we review the research procedure that has culminated in the development of a potential gene therapy for XLRP caused by RPGR mutations. Read More > |
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Research Trends
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| Why CAR NK Cell Therapy Research Is Quickly Growing |
| Aug 05, 2022 |
| What is CAR-T? The full name of CAR here is Chimeric Antigen Receptor, its structure includes extracellular domain, transmembrane domain, and an intracellular signal domain. Read More > |
