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| The First Artificial Chief Scientific Officer: AI Marvin |
| Nov 21, 2022 |
| Have you ever wondered what the future of science education looks like? Many envision a future of readily accessible science knowledge and facts presented by intelligent, interactive teachers. Read More > |
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Newsletter
Video
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| How to Search the Cyagen Knockout Catalog Models Resource |
| Aug 12, 2021 |
| Researchers may search for their desired gene KO and/or cKO model using either the website search bar, as shown in the video below, or by using our dedicated repository search page. Read More > |
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Newsletter
Video
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| Expert Webinar: Introduction to Genetically Engineered Rodent Models |
| Jun 15, 2021 |
| View our Expert Webinar to learn about cutting-edge genome editing technologies and application limitations of animal models - such as genetically modified mice and rats. Read More > |
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Video
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| Using CRISPR to Develop Knockout Mouse Models for Research |
| May 17, 2021 |
| Engineered nuclease-mediated genome editing, especially CRISPR, has emerged as a promising technology which can serve as an alternative to the conventional, embryonic stem (ES) cell homologous recombination-based generation of animal models. Read More > |
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Video
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| Comparing Mouse and Rat Models for Research |
| Mar 12, 2021 |
| As researchers seek the most accurate animal models for in vivo experiments, the availability of gene-editing technologies for developing both mouse and rat models has created more options than ever before. Murine genomes share great similarity with the human genome, which has made them fantastic models for a wide range human disease research. Read More > |
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Video
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| The PiggyBAC Transposon - Generating Transgenic Mice with Consistent Expression |
| Feb 23, 2021 |
| In most experiments, scientists will try to minimize the number of independent variables so as not to confuse the results of an experiment. Due to the varying level of gene expression achieved by traditional pronuclear injection (PNI), using the offspring from a transgenic mouse created via PNI may not be the best option. Read More > |
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Video
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| Pronuclear Injection-based Transgenic Mouse Model Generation |
| Feb 02, 2021 |
| Transgenic mice are important tools for scientists researching heritable traits and diseases in human populations. In traditional transgenics, the human gene (packaged in a transgenic construct) can be added to the mouse genome with a simple pronuclear injection into the male pronucleus. Read More > |
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Newsletter
Video
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| How Knockout Mice are Developed with Traditional Gene Targeting |
| Jan 15, 2021 |
| From the creation of the first knockout (KO) mouse, scientists have come extremely far. CRISPR technologies have quickly become a leading method used by genetic knockout scientists today, in part due to the method’s short turnaround. Read More > |
