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Most Popular
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Weekly Gene
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| The "Culprit" Of the Rare Diseases MCTD/OPMD - HNRNPC |
| Nov 16, 2021 |
| In this article, we review the hottest oncogene HNRNPC, hoping to give you insights on its role in rare disease development as a therapeutic target in MCTD research. Read More > |
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Weekly Gene
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| A Gene Related to Excitement- GRIA3 |
| Nov 09, 2021 |
| This week’s subject is the Glutamate Receptor, Ionotrophic, AMPA 3 (GRIA3) gene, which is closely related to the feeling of excitement. Read More > |
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Weekly Gene
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| NLRP3 and Familial Cold Autoinflammatory Syndrome |
| Nov 02, 2021 |
| The NLRP3 gene encodes NLR Family Pyrin Domain Containing 3 - a pyrin-like protein which contains a pyrin domain, a nucleotide binding site (NBS) domain, and a leucine-rich repeat sequence (LRR) motif. Read More > |
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Weekly Gene
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| An Important Target of the Deadly Lung Disease Idiopathic Pulmonary Fibrosis—CAV1 |
| Oct 26, 2021 |
| The CAV1 gene is responsible for encoding the Caveolin 1 (CAV1) protein, also called caveolin-1 (CAV-1), which belongs to the Caveolin family of integral membrane proteins. Read More > |
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Weekly Gene
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| Cockayne Syndrome B (CSB) and ERCC6 Gene |
| Oct 19, 2021 |
| Mutations in the excision and repair of cross-complementation group 6 (ERCC6) gene is known to result in Cockayne syndrome B (CSB), among some other disorders. Read More > |
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White Paper
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| White Paper: Gene Therapy Research and Humanized Mouse Models |
| Sep 26, 2021 |
| In Cyagen's exclusive White Paper, our experts briefly introduce the background of gene therapy for rare diseases and explore the applications of humanized mouse models for genetic diseases. Read More > |
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Newsletter
Video
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| How to Search the Cyagen Knockout Catalog Models Resource |
| Aug 12, 2021 |
| Researchers may search for their desired gene KO and/or cKO model using either the website search bar, as shown in the video below, or by using our dedicated repository search page. Read More > |
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Weekly Gene
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| Indispensable Genes for Lymphoid Cell V(D)J recombination & Immunotherapy - RAG1 & RAG2 |
| Aug 11, 2021 |
| The recombination-activating genes, Read More > |
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Newsletter
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| Choosing a Transfection Method to Improve Knockout Cell Line Generation Efficiency |
| Aug 05, 2021 |
| when using the CRISPR-Pro strategy in the construction of gene knockout (KO) cell lines, researchers might be troubled about choosing the specific model generation method from plasmid-based, viral delivery, and ribonucleoprotein (RNP) transfection. Read More > |
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Newsletter
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| FAQ: Cell Line Verification |
| Jul 30, 2021 |
| Cell lines verification is of the utmost importance. Skipping the verification step can lead to invalid research data, leading to lost time and money and retractions of publication. Herein, we have collected the Frequently Asked Questions on cell lines verification, hoping to provide research tips on cell line verification. Read More > |
