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Weekly Model
Marchf2 knockout mice and New Research Progress
Dec 31, 2021
In the previous article, we shared some diseases related to MARCHF2 (a.k.a. MARCH2). To this end, we introduce gene research' s next great example of this – Marchf2 knockout mice. Read More >
Weekly Gene
[Weekly Gene]—Will the MARCHF2 Gene be the Next Research Hotspot?
Dec 30, 2021
MARCH2 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19) Read More >
Research Trend
Application of CRISPR-Pro Gene Editing in CAR-T Cell Immunotherapy
Dec 29, 2021
The principle of CAR-T cell immunotherapy is to use genetic engineering methods to express chimeric antigen receptor (CAR) molecules on the surface of T cells. Read More >
Research Trend
Gene Therapy for Cardiovascular Disease: Application of Adeno-associated Viral Vector (AAV)
Dec 24, 2021
As of this year, there have been hundreds of recombinant adeno-associated virus (rAAV) gene therapy products approved to be marketed and entered into clinical trials worldwide. Why does AAV vector have such potential? Read More >
Weekly Model
Inpp5e Knockout Mice and New Research Model Progress
Dec 23, 2021
To study the mechanisms that are largely unknown, researchers use gene knockout or down-regulation to regulate the expression of mouse Inpp5e gene. Read More >
Weekly Gene
[Weekly Gene]—Targeting INPP5E in Rare Disease
Dec 21, 2021
INPP5E (Inositol Polyphosphate-5-Phosphatase E) is a Protein Coding gene. Diseases associated with INPP5E include Joubert Syndrome 1 and Mental Retardation, Truncal Obesity, Retinal Dystrophy, and Micropenis (MORM) Syndrome. Read More >
Research Trend
How to Validate Your CRISPR Knockout Cell Line?
Dec 20, 2021
When establishing a CRISPR-Pro-based knockout (KO) cell line model, it is important to validate the genetic modifications which have occurred. Read More >
Weekly Model
Mut-Stat3 Mice and New Research Model Progress
Dec 10, 2021
Gene research' s next great example– Mut-Stat3 mice  – which has the potential to alter the behavior of or even eliminate autosomal dominant hyper-IgE syndrome (AD-HIES). Read More >
Weekly Gene
[Weekly Gene]—Targeting STAT3 in Rare Disease
Dec 09, 2021
The STAT3 (Signal Transducer And Activator Of Transcription 3) gene is part of the STAT gene family. Read More >
Newsletter
LUCKY DRAW RESULTS
Dec 08, 2021
We are excited to announce that the winner (chosen by random selection) is Dr. Christopher Alexander, a Postdoctoral Fellow at the National Institutes of Health (NIH). Read More >