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Weekly Model
Ybx2 Mice and New Research Progress
Jan 28, 2022
The YBX2 gene is a germ cell-specific gene, and the phenotype of knockout mice is mainly focused on germ cells. These results indicate that suitable knockout mice are helping to study how the formation of germ cells are influenced by Ybx2. Read More >
Weekly Gene
[Weekly Gene] The Secret of YBX2's Regulatory Mechanisms
Jan 26, 2022
Although the gene YBX2 is not the direct cause of cancer, it seems to be inextricably linked to cancer, and the latest research shows that high YBX2 expression is unfavorable in prognosis of endometrial cancer. Read More >
Research Trend
Application of AAV-mediated Gene Therapy in Metabolic Disorders
Jan 24, 2022
The application of recombinant Adeno-Associated Virus (rAAV) drugs in clinical trials of metabolic diseases around the world is mainly concentrated among the following indications Read More >
Research Trend
Application of Gene Therapy in Mucopolysaccharidosis IVA (MPS IVA) (Part B)
Jan 20, 2022
In Part A, we describe how the Mucopolysaccharidosis IVA (MPS IVA, MPSIVA) rat model is generated. Please see Part B which we explore other promising applications of  AAV9-Galns treatments. Read More >
Weekly Model
Mouse Models of Adamts5 and Drug Development Progress
Jan 19, 2022
In the previous article, we shared the diseases related to ADAMTS5 gene mutations, such as osteoarthritis (OA) . Read More >
Animal breeding
Diagnostic Testing of Mouse for Infectious Agents
Jan 18, 2022
As most researchers know, the health of mice may affect the accuracy and reproducibility of experimental data when conducting experiments. Read More >
Weekly Gene
[Weekly Gene]—The 'culprit' of Osteoarthritis - ADAMTS5
Jan 14, 2022
On the 21st anniversary of the discovery of ADAMTS-5, this article looks at its deleterious effects in development of Osteoarthritis (OA). Read More >
Research Trend
The Ultimate Guide to Humanized Mice for Antibody Research
Jan 13, 2022
With the development of research on the impact of immunity and inflammation on cancer, the performance of humanized mice attract tremendous attention in cancer clinical research. Read More >
Research Trend
Application of Gene Therapy in Mucopolysaccharidosis IVA (MPS IVA) (Part A)
Jan 12, 2022
Mucopolysaccharidosis IVA (MPS IVA) - also known as Morquio Syndrome, type A - is inherited in an autosomal recessive manner and caused by mutations in the GALNS gene. Read More >
Animal breeding
How to Treat Ulcerative Dermatitis in Mice?
Jan 05, 2022
We will introduce new information about mouse breeding and health every week to provide education for aspiring mouse care experts. Read More >