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Newsletter
Breaking News
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| Cyagen's Partner InnoVec Receives US FDA Investigational New Drug Approval for IVB103 Clinical Trials |
| Aug 09, 2024 |
| On July 26, 2024, InnoVec's IVB103 injection received early Investigational New Drug (IND) approval from the U.S. Food and Drug Administration (FDA), which may now proceed to the clinical trial phase. Read More > |
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Research Trends
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| Adipoq-iCre Mice for Conditional Gene Targeting of Adipose Tissues & Fluorescent Detection Data |
| Aug 02, 2024 |
| In the realm of scientific research, particularly in studies focusing on fat cells and metabolic diseases, accurate and efficient fluorescent detection is essential. Read More > |
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Research Trends
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| Improving Pancreas-Specific Cre Mouse Lines with the Pdx1-CreERT2 Mouse Model |
| Jul 29, 2024 |
| The Cre-Lox system allows for gene knockout/knockin in specific cells/tissues, with the timing of its expression is determined by the promoter. Read More > |
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Research Trends
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| Humanized Immune System Mice: An Effective Preclinical Model for Reproducing Human Immune-Tumor Interactions |
| Jul 19, 2024 |
| Humanized Immune System Mice (HIS mice) are developed by transplanting human immune system components into mice, resulting in animal models that partially or fully replicate human immune system functions. Read More > |
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Research Trends
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| Highly Efficient Human NK Cell Immune Reconstitution Mouse Models: NKG-hIL15 & huHSC-NKG-hIL15 Mice |
| Jul 12, 2024 |
| Immunotherapy works by mobilizing immune cells within the body to enhance the immune system's ability to recognize, kill, and eliminate tumor cells. Given the differences between the immune systems of mice and humans, immunotherapies are typically evaluated in preclinical studies using humanized immune system (HIS) mouse models. Read More > |
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Research Trends
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| Hope for "Butterfly Children"—New Models in Research on Dystrophic Epidermolysis Bullosa (DEB) |
| Jul 05, 2024 |
| In everyday life, hugging is a way for people to express love and kindness. However, for individuals with Epidermolysis Bullosa (EB), this simple act of intimacy can cause immense pain. Read More > |
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Research Trends
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| HFD+CCl4-Induced Metabolic Dysfunction-Associated Steatohepatitis (MASH/NASH) Mice |
| Jun 28, 2024 |
| Metabolic dysfunction-associated steatohepatitis (MASH), previously referred to as nonalcoholic steatohepatitis (NASH), is a chronic liver disease. This condition frequently arises from metabolic irregularities like obesity or diabetes, leading to an accumulation of fat in the liver, which can become toxic and cause inflammation. Read More > |
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Research Trends
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| Recommended Model | Fabry Disease (FD) Research Model - Gla-KO Mice |
| Jun 21, 2024 |
| Fabry Disease (FD) is a rare genetic disorder categorized as a lysosomal storage disease (LSD). It is caused by a deficiency in the activity of the lysosomal enzyme alpha-galactosidase A (α-GalA), leading to the accumulation of its metabolic substrate, Read More > |
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Research Trends
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| Beyond Obesity Research: B6-hGDF15 Humanized Mice for Tumor, Diabetes, Morning Sickness, and Cardiovascular Studies |
| Jun 17, 2024 |
| Obesity is a major global health issue, and the discovery of new targets and the development of new therapies have always been focal points for researchers and pharmaceutical companies. Read More > |
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Research Trends
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| Inflammatory Bowel Disease Research Model—BALB/c-Il10 KO Mice for Studying Crohn's Disease & Ulcerative Colitis |
| Jun 11, 2024 |
| The recent news that Kate Middleton, the Duchess of Cambridge, might be suffering from Crohn's Disease (CD) has drawn widespread public attention, leading more people to become aware of this condition, often referred to as "green cancer." Read More > |
