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Research Trends
Circumventing Difficulties in Dynamic Monitoring of Orthotopic Tumor Transplantation Models with In Vivo Bioluminescent Imaging
Jan 12, 2024
Compared to the traditional method of euthanizing animals in batches to obtain experimental data, real-time bioluminescence imaging (BLI) technology allows for qualitative and quantitative observations at the cellular and molecular levels of a living organism. Read More >
Ten Deadly Sins of Rare Diseases
Unraveling Rare Diseases: Researching Hotspot Pathogenic Mutations in Humanized Models
Dec 29, 2023
Welcome to the 'Ten Deadly Sins of Rare Diseases' column, where we decode the pathogenic mechanisms of rare diseases, industry research progress (e.g. gene therapy), and innovative pre-clinical strategies to drive translational research results (such as model construction and drug screening, etc.). Read More >
Research Trends
Breaking Stereotypes: Diabetes Research, GLP-1, and the Roadmap for Preclinical Studies
Dec 18, 2023
On November 14th, World Diabetes Day serves as a global call to action to confront the complexities of diabetes, a condition that often grapples with various stereotypes and misconceptions. It's a common misbelief that only overweight individuals are at risk of diabetes or that young people need not be concerned about it. Read More >
Research Trends
Age-Related Health Challenges in Lab Rats: A Comprehensive Examination
Dec 11, 2023
In this issue, we will be discussing another factor that is often overlooked but can significantly impact rat health — age. Get ready to learn more about the impacts of rodent age on health! Read More >
Research Trends
High-Quality Adeno-Associated Virus (AAV) Packaging
Dec 04, 2023
In the rapidly advancing field of gene therapy, the efficiency and reliability of adeno-associated virus (AAV) vectors play a pivotal role in driving groundbreaking research and therapeutic developments. At Cyagen, we stand at the forefront of this revolution, offering a comprehensive suite of AI-assisted AAV production services designed to streamline your experimental process and elevate your research to new heights. Our commitment to excellence extends across the entire spectrum of AAV production, from vector design and construction to virus packaging, purification, expression analysis, and functional validation. Read More >
Ten Deadly Sins of Rare Diseases
Unraveling the Genetic Tapestry of Angelman Syndrome: Decoding Maternal Genetic Abnormalities Behind the 'Happy Puppet' Phenomenon. [Ten Deadly Sins of Rare Diseases Ⅶ]
Nov 24, 2023
Welcome to the 'Ten Deadly Sins of Rare Diseases' Column, where we delve into the intricate world of rare diseases, industry breakthroughs in gene therapy, and innovative pre-clinical research strategies to drive translational successes. In this edition, we shine a spotlight on Angelman Syndrome (AS), a rare disorder linked to the imprinted gene UBE3A. Read More >
Research Trends
Ensuring Optimal Well-being for Lab Mice: A Guide to Daily Observation and Care
Nov 21, 2023
In the realm of biomedical research, mice are widely used for various experiments. To guarantee their well-being and enhance the precision of experiments, it is imperative to dedicate time and attention to their daily care. This article delves into the nuances of maintaining mouse health, shedding light on key aspects of daily care and observation that significantly impact the success of scientific endeavors. Read More >
Ten Deadly Sins of Rare Diseases
Application of Humanized Mouse Models in DNA Repeat Expansion Diseases [Ten Deadly Sins of Rare Diseases Ⅵ]
Nov 15, 2023
Enter the 'Ten Deadly Sins of Rare Diseases' column to unlock the mechanisms of rare disease occurrence and development, industry research advancements (such as gene therapy), and innovative strategies for advancing clinical outcomes (including model construction and drug screening). Read More >
Research Trends
What are rare immunological diseases? Exploring the Advantages of NKG Severe Immunodeficient Mice
Nov 03, 2023
Do you recall the famous "Bubble Boy"? Poor David suffered from Severe Combined Immunodeficiency (SCID), which made him incapable of combatting any bacteria or viruses, forcing him to spend his entire life in a sterile environment. Shortly after his birth, doctors placed him into a sterile bubble, hence the term "Bubble Boy" for people with similar conditions. Today, let's delve deeper into immunodeficiency disorders. Read More >
Research Trends
Congenital Genetic Abnormalities & Related Phenotypes in Rat Models of Human Diseases
Oct 27, 2023
In addition to factors related to routine husbandry practices, rats are also susceptible to various genetic diseases, known as congenital genetic abnormalities. Today, we will introduce some congenital genetic abnormalities commonly seen in rats. Read More >