
IDEAS TO IND — YOUR PATHWAY TO DISCOVERY
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Animal
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Pioneering life science advancements to deliver real-world health solutions.
Our Solutions: Integrated preclinical services, including:
- ● Cell & animal model development and viral packaging.
- ● Expert-led preclinical studies.
Your Outcome: Seamlessly translating innovative research into actionable results and successful IND applications.
Citation Database
Molecular Therapy: Methods & Clinical Development, March, 2025
Intracranial AAV administration dose-dependently recruits B cells to inhibit the AAV redosing
【Other】
Gut, February, 2025
E-twenty-six-specific sequence variant 5 (ETV5) facilitates hepatocellular carcinoma progression and metastasis through enhancing polymorphonuclear myeloid-derived suppressor cell (PMN-MDSC)-mediated immunosuppression
【Other】
Cell Death & Disease, February, 2025
Mcm5 mutation leads to silencing of Stat1-bcl2 which accelerating apoptosis of immature T lymphocytes with DNA damage
【Other】
Molecular Therapy, February, 2025
Single-cell data-driven design of armed oncolytic virus to boost cooperative innate-adaptive immunity against cancer
【Other】
Resource Library
BLOG & INSIGHTS
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Understanding Athymic Nude Mice: Foxn1 Genetics, Immunology and Oncology CDX Applications
Dive into the essential role of athymic nude mice in biomedical research. This comprehensive guide unravels the Foxn1 genetic mutation, explores their unique T-cell deficient immunological profile, and highlights their indispensable utility in validating preclinical oncology therapies through robust Cell-Derived Xenograft (CDX) models.
April 20, 2026
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UPCOMING EVENT
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EASL Congress 2026
Cyagen will attend EASL Congress 2026 in Barcelona from May 27–30, where we will showcase our capabilities across key hepatology-focused areas, including MASLD/MASH and liver fibrosis, oncology and immuno-oncology, hepatic cancers. Our team will be available to discuss how researchers and biotech partners are leveraging Cyagen’s humanized model platforms, antibody discovery capabilities, and end-to-end CRO services to move more confidently from target validation to in vivo proof-of-concept
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WEBINAR
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Interferons: From Basic Biology to Translational Applications
Interferons (IFNs) are pivotal cytokines orchestrating antiviral defense, immune modulation, and oncological responses. However, despite decades of clinical application, their broad therapeutic utility is frequently hindered by systemic toxicity, off-target effects, and unpredictable patient heterogeneity.This webinar introduces the fundamental biology of interferons, addressing the critical question of why there are so many interferon subtypes and exploring their unique biological significance.
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