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Knockin Cell Lines
Knockin Cell Lines
Drive your experiments using site-specific modifications that support gene regulation studies, disease modeling, and drug screening. Our knockin cell lines offer consistent insertion of reporters, point mutations, or fusion tags, delivering validated solutions for actionable insights in your next project.
HUGO-GTTM: Revolutionizing Humanized Mouse Models
HUGO-GT™ (Rare Disease Research)
Accelerating Drug Discovery with Precise Genome-Wide Humanization Experience accuracy and reliability in preclinical studies with HUGO-GT™ models, powered by our proprietary TurboKnockout-Pro technology.
Knockin Mice
Knockin Mice
Cyagen's knockin mice offer precise genetic modifications tailored to diverse research needs, including humanized and large-fragment knockins across C57BL/6 or BALB/c strains. These models enable effective disease modeling and functional studies by replicating human gene functions within a mouse, providing reliable, study-ready cohorts to fast-track preclinical research.
Transgenic Rats
Transgenic Rats
Discover Cyagen's advanced transgenic rat services, utilizing cutting-edge methods for precise genetic modifications. Our established Regular and PiggyBac transgenesis techniques offer robust and dependable gene integration solutions, perfect for complex disease modeling and functional studies.
Knockin Rats
Knockin Rats
Cyagen's knockin rats provide targeted genetic alterations to meet complex research demands, encompassing everything from point mutations to large-fragment knockins. These rats are invaluable for modeling human diseases and studying gene function, offering robust, study-ready cohorts that accelerate the pace of preclinical research.
Transgenic Mice
Transgenic Mice
Discover Cyagen's transgenic mouse services, offering both Regular and PiggyBac methods for diverse research applications. Benefit from our mature technology for gene integrations and tailored modifications that enhance disease modeling and functional studies, ensuring reliable results.
Targeted Gene Editing
Targeted Gene Editing
Achieve precise genetic modifications in mice and rats with fast, cost-effective, and high-efficiency gene editing – powered by AI-optimized guide design and proprietary delivery techniques.
Knockout Rats
Knockout Rats
Explore Cyagen's knockout rat services, utilizing advanced Targeted Gene Editing technology for precise and efficient genome editing. Our knockout rats are vital for studying human diseases and advancing drug development, ensuring impactful research outcomes.
PiggyBac Transgenesis
PiggyBac Transgenesis
Cyagen’s PiggyBac transgenesis platform enables efficient generation of stable, single-copy transgenic rodent models with consistent gene expression. It offers a reliable and cost-effective alternative for studying gene function and overexpression in vivo.
BAC Transgenesis
BAC Transgenic
BAC (Bacterial Artificial Chromosome) transgenesis enables insertion of large genomic fragments—such as full genes with regulatory elements—into rodent genomes, ensuring faithful expression and supporting complex loci that are hard to replicate by other methods.
Animal Models
C57BL/6NCya-Tnfaip8em1flox/Cya
Tnfaip8 is located on chromosome 18 of mice. SgRNA and ssDNA were designed using Nuclease Technology; Tnfaip8 conditional knockout mice were obtained by high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Afap1l1em1flox/Cya
Afap1l1 is located on chromosome 18 of mice. SgRNA and ssDNA will be designed using Nuclease Technology; Afap1l1 conditional knockout mice will be obtained by high-throughput electroporation of fertilized eggs. After sexual maturity, sperm will be collected for cryopreservation.
C57BL/6JCya-Smim3em1flox/Cya
Smim3 is located on chromosome 18 of mice. SgRNA and ssDNA will be designed using Nuclease Technology; Smim3 conditional knockout mice will be obtained by high-throughput electroporation of fertilized eggs. After sexual maturity, sperm will be collected for cryopreservation.
C57BL/6JCya-Hmgxb3em1flox/Cya
Hmgxb3 is located on chromosome 18 of mice. SgRNA and ssDNA will be designed using Nuclease Technology; Hmgxb3 conditional knockout mice will be obtained by high-throughput electroporation of fertilized eggs. After sexual maturity, sperm will be collected for cryopreservation.
C57BL/6JCya-Kctd1em1flox/Cya
Kctd1 is located on chromosome 18 of mice. SgRNA and ssDNA will be designed using Nuclease Technology; Kctd1 conditional knockout mice will be obtained by high-throughput electroporation of fertilized eggs. After sexual maturity, sperm will be collected for cryopreservation.
C57BL/6JCya-Slc39a3em1flox/Cya
Slc39a3 is located on chromosome 10 of mice. SgRNA and ssDNA were designed using Nuclease Technology; Slc39a3 conditional knockout mice were obtained by high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Arap3em1flox/Cya
Arap3 is located on chromosome 18 of mice. SgRNA and ssDNA will be designed using Nuclease Technology; Arap3 conditional knockout mice will be obtained by high-throughput electroporation of fertilized eggs. After sexual maturity, sperm will be collected for cryopreservation.
C57BL/6JCya-Slc39a6em1flox/Cya
Slc39a6 is located on chromosome 18 of mice. SgRNA and ssDNA will be designed using Nuclease Technology; Slc39a6 conditional knockout mice will be obtained by high-throughput electroporation of fertilized eggs. After sexual maturity, sperm will be collected for cryopreservation.
C57BL/6JCya-Gramd2bem1flox/Cya
Gramd2b is located on chromosome 18 of mice. SgRNA and ssDNA were designed using Nuclease Technology; Gramd2b conditional knockout mice were obtained by high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Me2em1flox/Cya
Me2 is located on chromosome 18 of mice. SgRNA and ssDNA will be designed using Nuclease Technology; Me2 conditional knockout mice will be obtained by high-throughput electroporation of fertilized eggs. After sexual maturity, sperm will be collected for cryopreservation.
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