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Unlock the full potential of your preclinical research with Cyagen Biosciences. Our integrated solutions span from custom cell and animal model development through preclinical experiments, ensuring every phase of your project is expertly handled. Discover how we can help transform your innovative ideas into actionable outcomes and help translate your research discoveries into INDs.
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Elevate your research with our Next-Generation HUGO-GTTM Humanization Models.
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Genetically Engineered Animals
Cyagen provides knockout, knockin, and transgenic models with high genetic precision to support research in genetics, pharmacology, and disease modeling.
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New to Cyagen? Now’s your chance to access premium iPSC gene editing services at half the cost. From knockout to overexpression models, this limited-time offer is exclusive to first-time cell line clients across North America, Europe, and Asia-Pacific. Only 100 spots available—apply early.
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Cyagen's gene editing services are top-notch. We have successfully generated multiple knockout models with their help.
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Yale University
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University of Michigan
Citation Database
Molecular Therapy: Methods & Clinical Development, March, 2025
Intracranial AAV administration dose-dependently recruits B cells to inhibit the AAV redosing
【Other】
Gut, February, 2025
E-twenty-six-specific sequence variant 5 (ETV5) facilitates hepatocellular carcinoma progression and metastasis through enhancing polymorphonuclear myeloid-derived suppressor cell (PMN-MDSC)-mediated immunosuppression
【Other】
Cell Death & Disease, January, 2025
CKMT1 deficiency contributes to mitochondrial dysfunction and promotes intestinal epithelial cell apoptosis via reverse electron transfer-derived ROS in colitis
【Cell Biology】
Nature Cancer, January, 2025
Palmitoylation of GPX4 via the targetable ZDHHC8 determines ferroptosis sensitivity and antitumor immunity
【Neurobiology】
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Unveiling New Frontiers in Vascular Disease Research: Novel Humanized Mouse Models for Angiogenesis
Unveiling New Frontiers in Vascular Disease Research: Novel Humanized Mouse Models for Angiogenesis
Vascular diseases, from cancer to diabetic retinopathy, pose major global health challenges. Angiopoietin-2 (ANG2), a key regulator of vascular homeostasis, is closely linked to disease progression. The clinical success of bispecific antibodies targeting ANG2 and VEGFA, such as Roche's Faricimab, highlights the urgent need for predictive animal models to advance drug discovery and development.
August 09, 2025
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Meet Cyagen at Bio Japan 2025 in Yokohama—where global biotech meets preclinical innovation, and we showcase how our models accelerate drug R&D.
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Harnessing GLP-1 and Amylin Power for Obesity Care with Reliable Preclinical In Vivo Models
Harnessing GLP-1 and Amylin Power for Obesity Care with Reliable Preclinical In Vivo Models
GLP-1 and amylin are reshaping obesity drug development with their synergistic weight loss effects. Join our webinar to explore how Cyagen’s validated in vivo models and pharmacology services can support your preclinical research and fast-track anti-obesity drug discovery.
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Taconic and Cyagen Collaborate to Streamline Access to Preclinical Mouse and Rat Models
August 04, 2025
YIMA and ZIP Solutions Announce Strategic Co-Marketing Agreement for Gene Therapy
June 12, 2025
HistoWiz and Cyagen Collaborate to Streamline Histopathology for Academic and Preclinical Mouse and Rat Model Research
June 10, 2025
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