Logo
Homepage
Explore Our Models
My Cart
Contact
Subscribe
Models
HUGO Series 🌟
HUGO-GT™ (Rare Disease Research)
HUGO-Ab™ (Antibody Discovery)
MouseAtlas Model Library
Research Models
Cre Mouse Lines
Humanized Target Gene Models
Metabolic Disease Models
Ophthalmic Disease Models
Neurological Disease Models
Autoimmune Disease Models
Immunodeficient Mouse Models
Humanized Immune System Mouse Models
Oncology & Immuno-oncology Models
Covid-19 Mouse Models
Cell Line Models
Knockout Cell Line Product Catalog
Tumor Cell Line Product Catalog
AAV Standard Product Catalog
Services
Preclinical Efficacy
Neuroscience
Alzheimer's Disease (AD)
Parkinson's Disease (PD)
Huntington's Disease (HD)
Ophthalmology
Oncology
Metabolic & Cardiovascular Diseases
Autoimmune & Inflammatory
Genetically Engineered Animals
Knockout Mice
Transgenic Mice
Knockin Mice
Knockout Rats
Knockin Rats
Transgenic Rats
Model Generation Techniques
Turboknockout<sup>®</sup> Gene Targeting
ES Cell Gene Targeting
Targeted Gene Editing
Regular Transgenic
PiggyBac Transgenesis
BAC Transgenic
Breeding & Supporting Services
Breeding Services
Cryopreservation & Recovery
Phenotyping Services
BAC Modification
Virus Packaging
Adeno-associated Virus (AAV) Packaging
Lentivirus Packaging
Adenovirus Packaging
Custom Cell Line Services
Induced Pluripotent Stem Cells (iPSCs)
Knockout Cell Lines
Knockin Cell Lines
Point Mutation Cell Lines
Overexpression Cell Lines
Modalities
Gene Therapy
AI-Powered AAV Discovery
Oligonucleotide Therapy
Cell Immunotherapy
Resources
Promotion
Events & Webinars
Newsroom
Blogs & Insights
Resource Vault
Reference Databases
Peer-Reviewed Citations
Rare Disease Data Center
AbSeek
Cell iGeneEditor™ System
OriCell
About Us
Corporate Overview
Facility Overview
Animal Health & Welfare
Health Reports
Our Partners
Careers
Contact Us
Login
Ideas to lND - Your Pathway to Discovery
Empowering Preclinical Innovation
Unlock the full potential of your preclinical research with Cyagen Biosciences. Our integrated solutions span from custom cell and animal model development through preclinical experiments, ensuring every phase of your project is expertly handled. Discover how we can help transform your innovative ideas into actionable outcomes and help translate your research discoveries into INDs.
OK to Switch
Receive Up to 15 Free NKG Mice for Trial
Explore
Innovative Solutions & Trusted Products
Genetically Engineered Animals
Cyagen provides knockout, knockin, and transgenic models with high genetic precision to support research in genetics, pharmacology, and disease modeling.
Comprehensive Research Models
Our humanized, knockout, and disease-specific mice closely mimic human conditions, empowering your preclinical studies from rare diseases to oncology.
Custom Cell Lines
Cyagen delivers custom iPSC, knockout, and knockin cell lines for genetic studies, drug screening, and therapeutic development.
Virus Packaging Solutions
We offer AAV, lentivirus, and adenovirus packaging for gene therapy, vaccine R&D, and gene editing applications.
Antibody Therapy CRO Services
Cyagen accelerates antibody drug discovery with fully human antibody mice and AI-powered screening, supporting you from discovery to validation.
Animal Quality
We uphold the highest standards in animal welfare and qualty in our AAALAC-accredited faciities, ensuring ethical research practices.
Special Promotions & Discounts
See All Promotions
Free Trial
OK to Switch - Introducing the Locally Bred NKG Mice
Cyagen is inviting researchers to experience the benefits of our NKG mice breed in the US. This "OK to Switch" offer is designed to help you easily transition from your current models with zero risk and gap.
Explore
Special Offer
Cell Line Project Special Offer
Get guaranteed, publication-ready cell lines without the endless troubleshooting. For a limited time, let our experts deliver your custom model for 50% less
Explore
Award
Cyagen Trailblazer Grant Award – Funding the Frontier of Model Generation
The Cyagen Trailblazer Grant Award (CTGA) 2025 is a global funding initiative supporting breakthroughs in biomedical research through the development of high-impact custom animal models. This year, Cyagen will provide up to $1 million USD in model generation funding to 50 research teams worldwide. Eligible research spans diverse areas, including cancer, neurological, cardiovascular, metabolic, immunological, and rare diseases. Researchers are invited to submit proposals and join an international community driving the future of preclinical research
Explore
Your Partners in Preclinical Progress
Your Partners in Preclinical Progress
19
Years of Genetic Innovation
7,000
Global Bioscience Partners
50,000
Mouse & Rat Models Delivered
10,925
SCI Journal Citations
250,000
SPF Animals in AAALAC-Accredited Facilities
Cyagen's gene editing services are top-notch. We have successfully generated multiple knockout models with their help.
Dr. Sarah Lee
Yale University
The technical support from Cyagen has been exceptional. They have gone above and beyond to ensure our experiments are successful.
Dr. Edward Green
University of Michigan
Citation Database
Molecular Therapy: Methods & Clinical Development, March, 2025
Intracranial AAV administration dose-dependently recruits B cells to inhibit the AAV redosing
【Other】
Gut, February, 2025
E-twenty-six-specific sequence variant 5 (ETV5) facilitates hepatocellular carcinoma progression and metastasis through enhancing polymorphonuclear myeloid-derived suppressor cell (PMN-MDSC)-mediated immunosuppression
【Other】
Cell Death & Disease, February, 2025
Mcm5 mutation leads to silencing of Stat1-bcl2 which accelerating apoptosis of immature T lymphocytes with DNA damage
【Other】
Molecular Therapy, February, 2025
Single-cell data-driven design of armed oncolytic virus to boost cooperative innate-adaptive immunity against cancer
【Other】
Resource Library
BLOG & INSIGHTS
More Insights
Humanized ABCA4 Models Advance RNA & Gene Editing
Humanized ABCA4 Models Advance RNA & Gene Editing
Designed for translational research, Cyagen’s B6-hABCA4 and c.5461-10T>C mouse models enable preclinical testing of base editing, antisense oligonucleotides, and RNA editing therapies for Stargardt disease. These models offer precise genomic alignment with human ABCA4 mutations, enhancing clinical relevance.
October 16, 2025
Schedule Meeting
UPCOMING EVENT
More
Frontiers in Cancer Science 2025
Frontiers in Cancer Science 2025
Cyagen will be attending Frontiers in Cancer Science 2025 from November 5–7 in Singapore, where our experts will be on hand to discuss your drug development plans and introduce you to our advanced mouse models and comprehensive preclinical research services. We look forward to connecting with you!
Schedule Meeting
WEBINAR
More
Expanding the Cre-lox Toolbox: Advanced Targeting and a Comprehensive Repository of Conditional Mouse Models
Expanding the Cre-lox Toolbox: Advanced Targeting and a Comprehensive Repository of Conditional Mouse Models
This webinar will provide an understanding of Cyagen's innovative design pipeline, strategies for verifying Cre expression and specificity, and Taconic's best practices for breeding and maintaining Cre x floxed lines to ensure experimental reproducibility and translational relevance across research and development applications.
Schedule Meeting
FEATURED NEWS
Taconic and Cyagen Collaborate to Streamline Access to Preclinical Mouse and Rat Models
August 04, 2025
Model Library
Model Library
Resources
Resources
Animal Quality
Animal Quality
Get Support
Get Support
Address:
2255 Martin Avenue, Suite E Santa Clara, CA 95050-2709, US
Tel:
800-921-8930 (8-6pm PST)
+1408-963-0306 (lnt’l)
Fax:
408-969-0336
Email:
inquiry@cyagen.com
Models
HUGO-Ab™ (Antibody Discovery)HUGO-GT™ (Rare Disease Research)MouseAtlas Model LibraryResearch Models
Services
NeuroscienceOphthalmologyOncologyMetabolic & Cardiovascular DiseasesAutoimmune & Inflammatory
About Us
Corporate OverviewFacility OverviewAnimal Health & WelfareHealth ReportsOur PartnersCareersContact Us
Social Media
Disclaimer: Pricing and availability of our products and services vary by region. Listed prices are applicable to the specific countries. Please contact us for more information.
Copyright © 2025 Cyagen. All rights reserved.
Privacy Policy
Site Map
Stay Updated with the Latest from Cyagen
Get the latest news on our research models, CRO services, scientific resources, and special offers—tailored to your research needs and delivered straight to your inbox.
Full Name
Email
Organization
Country
Areas of Interest
Main Area of Research