Ace2 KO
Product Type
Age
Genotype
Sex
Quantity
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Basic Information
Model Name
Ace2 KO
Product ID
C001228
Gene Name
Background
C57BL/6JCya
Gene Alias
2010305L05Rik
Classification
Infectious Disease Models
NCBI ID
Phenotype
Chromosome
X
Document
Note: When using this mouse strain in a publication, please cite “Ace2 KO mice (Catalog C001228) were purchased from Cyagen.”
Strain Description
This strain is a mouse Ace2 gene knockout model that uses gene editing technology to knock out the homologous gene of human ACE2 in mice. The knockout of the Ace2 gene will result in the absence of ACE2 protein expression, and this model can be used for the study of COVID-19. The homozygous Ace2-KO mice are viable and fertile.
Application Area
Research on Cardiovascular and Cardiac Contraction
Research on Renal Function and Colitis
Research on COVID-19 and SARS
Validation Data