huHSC-NKG
Product Type
Age
Genotype
Sex
Quantity
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Basic Information
Model Name
huHSC-NKG
Product ID
C001328
Gene Name
Background
NKG
Gene Alias
gc; p64; [g]c; CD132; gamma(c)
Classification
Immunodeficient Mouse Models,Humanized Immune System Models
NCBI ID
Phenotype
--
Chromosome
X
Document
Note: When using this mouse strain in a publication, please cite “huHSC-NKG mice (Catalog C001328) were purchased from Cyagen.”
Strain Description
huHSC-NKG mice are immune system humanized mouse models constructed by transplanting human hematopoietic stem cells (HSC) into NKG mice after sub-lethal dose irradiation. This model has a long lifespan and can successfully reconstitute a variety of immune cells. Furthermore, huHSC-NKG mice typically do not develop graft-versus-host disease (GvHD) and the reconstitution period can be lengthy.
Application Area
Long-term research in the fields of tumor immunity, hematopoiesis, and gene therapy for hematologic and infectious diseases.
Validation Data