huPBMC-NKG
Product Type
Age
Genotype
Sex
Quantity
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Basic Information
Model Name
huPBMC-NKG
Product ID
C001329
Gene Name
Background
NKG
Gene Alias
gc; p64; [g]c; CD132; gamma(c)
Classification
Immunodeficient Mouse Models,Humanized Immune System Models
NCBI ID
Phenotype
Chromosome
X
Document
Note: When using this mouse strain in a publication, please cite “huPBMC-NKG mice (Catalog C001329) were purchased from Cyagen.”
Strain Description
PBMC humanized mice refer to the immune system humanized mouse model constructed by transplanting human peripheral blood mononuclear cells (PBMC) into immunodeficient mice (such as NKG). NKG mice transplanted with PBMC (huPBMC-NKG) have high efficiency and fast immune reconstitution. Human T cells generated after PBMC injection will attack mouse recipient cells, resulting in graft-versus-host disease (GvHD), so this model can be used to evaluate GvHD drugs.
Application Area
Short-term studies requiring mature T cells in the fields of tumor immunity, Hematopoiesis, and gene therapy for hematologic and infectious diseases.
Validation Data