H11-CAG-LSL-hMYC-IRES-EGFP
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Basic Information
Model Name
H11-CAG-LSL-hMYC-IRES-EGFP
Product ID
C001338
Gene Name
Background
C57BL/6JCya
Gene Alias
MRTL; MYCC; c-Myc; bHLHe39
Classification
Other Target Humanized Models
NCBI ID
Phenotype
Chromosome
8
Document
Note: When using this mouse strain in a publication, please cite “H11-CAG-LSL-hMYC-IRES-EGFP mice (Catalog C001338) were purchased from Cyagen.”
Strain Description
This strain carries a CAG promoter-driven LSL-hMYC-IRES-EGFP conditional overexpression structure inserted at the H11 safe harbor locus and overexpresses the human MYC gene in specific tissues or cells after mating with tissue-specific Cre mice.
Application Area
The model can be mated with different tissue-specific Cre mice for the study of tumors in different tissues or organs
Validation Data