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B6-hATXN3
Product ID:
C001398
Background:
C57BL/6NCya
Documents:
Click here to download >
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Basic Information
Model Name
B6-hATXN3
Product ID
C001398
Gene Name
ATXN3
Background
C57BL/6NCya
Gene Alias
AT3; JOS; MJD; ATX3; MJD1; SCA3
Classification
Full-Gene Humanized Models,Neurological Disease Models
NCBI ID
4287
Phenotype
MGI:1099442
Chromosome
14
More
Rare Disease Data Center >>
Document
Click here to download >>
Note
Note: When using this mouse strain in a publication, please cite “B6-hATXN3 mice (Catalog C001398) were purchased from Cyagen.”
Strain Description
This strain is a mouse Atxn3 gene humanized model that can be used for research on Spinocerebellar ataxia type 3 (SCA3). The homozygous B6-hATXN3 mice are viable and fertile.
Application Area
Area
Research on Machado-Joseph disease (MJD, SCA3)
Area
Preclinical evaluation of ATXN3-targeted drugs
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