B6-hALB (HSA)
Product Type
Age
Genotype
Sex
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Basic Information
Model Name
B6-hALB (HSA)
Product ID
C001492
Gene Name
Background
C57BL/6NCya
Gene Alias
HSA; FDAHT; PRO0883; PRO0903; PRO1341
Classification
Full-Gene Humanized Models
NCBI ID
Phenotype
Chromosome
4
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Note: When using this mouse strain in a publication, please cite “B6-hALB (HSA) mice (Catalog C001492) were purchased from Cyagen.”
Strain Description
This strain is a humanized mouse model of the Alb gene, obtained by in situ replacement of the entire mouse Alb gene sequence, including the UTR region, with the human ALB gene sequence. This model can be used for the development of ALB-targeted drugs, as well as for the research and development of drugs using HSA as a carrier, and for in vivo pharmacodynamics and pharmacokinetics studies, including albumin-drug conjugates or albumin-binding prodrugs.
Application Area
Development and evaluation of ALB-targeted drugs
Design and evaluation of albumin carrier drugs
Research on ALB-related metabolic diseases
Validation Data