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FVB-Abcb1a & Abcb1b DKO (Mdr1a/b KO)
Product ID:
C001493
Background:
FVB/NJCya
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Strain Description
This strain is an MDR1 knockout model, in which the human ABCB1 gene's homologous genes, Abcb1a and Abcb1b, were knocked out in mice using gene editing technology. This model lacks the expression of MDR1 protein and can be used for research in areas such as blood-brain barrier permeability-related diseases and multidrug resistance of anti-tumor drugs.
Application Area
Area
Research on blood-brain barrier permeability-related diseases
Area
Research on multidrug resistance of anti-tumor drugs
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