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B6-hABCA4
Product ID:
C001551
Background:
C57BL/6JCya
Documents:
Click here to download >
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Genotype
Sex
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Price:
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Basic Information
Model Name
B6-hABCA4
Product ID
C001551
Gene Name
ABCA4
Background
C57BL/6JCya
Gene Alias
FFM; RMP; ABCR; RP19; STGD; ABC10; ARMD2; CORD3; STGD1
Classification
Full-Gene Humanized Models,Ophthalmic Disease Models
NCBI ID
24
Phenotype
MGI:109424
Chromosome
1
More
Rare Disease Data Center >>
Document
Click here to download >>
Note
Note: When using this mouse strain in a publication, please cite “B6-hABCA4 mice (Catalog C001551) were purchased from Cyagen.”
Strain Description
This strain is a mouse Abca4 gene humanized model and can be used to research STGD, CRD, and RP. The homozygous B6-hABCA4 mice are viable and fertile. In addition, based on the independently developed TurboKnockout fusion BAC recombination technology, Cyagen can also generate hot mutation (ABCA4 c.5461-10 T to C) models based on this strain and provide customized services for specific mutations to meet the experimental needs in pharmacology and other fields.
Application Area
Area
Research on Stargardt Disease (STGD)
Area
Research on Cone-rod Dystrophy (CRD)
Area
Research on Retinitis Pigmentosa (RP)
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