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B6-hVEGFA
Product ID:
C001555
Background:
C57BL/6JCya
Documents:
Click here to download >
Product Type
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Genotype
Sex
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Price:
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Basic Information
Model Name
B6-hVEGFA
Product ID
C001555
Gene Name
VEGFA
Background
C57BL/6JCya
Gene Alias
VPF; VEGF; MVCD1; L-VEGF
Classification
Tumor Target Humanized Models,Cytokine Humanized Models,Full-Gene Humanized Models,Ophthalmic Disease Models
NCBI ID
7422
Phenotype
MGI:103178
Chromosome
6
More
Rare Disease Data Center >>
Document
Click here to download >>
Note
Note: When using this mouse strain in a publication, please cite “B6-hVEGFA mice (Catalog C001555) were purchased from Cyagen.”
Strain Description
The B6-hVEGFA mice were generated by replacing the mouse Vegfa gene sequence with the human VEGFA gene sequence, including the non-coding 3’ UTR region. This model expresses the human VEGFA protein. B6-hVEGFA mice can be used for mechanistic studies and efficacy evaluations of ophthalmic diseases such as Age-Related Macular Degeneration (AMD), Diabetic Retinopathy (DR), and corneal neovascularization, as well as for tumor development and cancer drug research.
Application Area
Area
Research on Age-Related Macular Degeneration (AMD)
Area
Research on Diabetic Retinopathy (DR)
Area
Research on corneal neovascular diseases
Area
Tumor development and cancer drug research
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