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B6-hC3/hTFRC (CDS)
Product ID:
C001608
Background:
C57BL/6JCya;C57BL/6NCya
Documents:
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Basic Information
Model Name
B6-hC3/hTFRC (CDS)
Product ID
C001608
Gene Name
C3, TFRC
Background
C57BL/6JCya;C57BL/6NCya
Gene Alias
ASP; C3a; C3b; AHUS5; ARMD9; CPAMD1; HEL-S-62p; T9; TR; TFR; p90; CD71; TFR1; TRFR; IMD46
Classification
Cytokine Humanized Models,Full-Gene Humanized Models,Ophthalmic Disease Models
NCBI ID
718, 7037
Phenotype
MGI:88227, MGI:98822
Chromosome
19
More
Rare Disease Data Center >>
Document
Click here to download >>
Note
Note: When using this mouse strain in a publication, please cite “B6-hC3/hTFRC (CDS) mice (Catalog C001608) were purchased from Cyagen.”
Strain Description
The B6-hC3/hTFRC (CDS) mouse model is a humanized model obtained by breeding B6-hC3 mice (Catalog No.: I001135) with B6-hTFRC (CDS) mice (Catalog No.: C001584). This model can be used for research on complement-mediated diseases, iron metabolism disorders, neurodegenerative diseases, and tumor development, aiding in studying C3/TFRC-targeted drugs.
Application Area
Area
Research on complement-mediated diseases, iron metabolism disorders, neurodegenerative diseases, and tumor development
Area
Development, screening, and efficacy evaluation of C3/TFRC-targeted therapies
Area
Research and evaluation of drug delivery across the blood-brain barrier (BBB)
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