Agxt KO
Product Type
Age
Genotype
Sex
Quantity
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Basic Information
Model Name
Agxt KO
Product ID
C001703
Gene Name
Background
C57BL/6NCya
Gene Alias
AGT; SPT; Agt1; Agxt1
Classification
Metabolic Disease Models,Rare Disease Models
NCBI ID
Phenotype
Chromosome
1
Document
Note: When using this mouse strain in a publication, please cite “Agxt KO mice (Catalog C001703) were purchased from Cyagen.”
Strain Description
The Agxt KO mouse is a gene knockout model created using gene-editing techniques to knock out the coding sequence of the Agxt gene (the homolog of the human AGXT gene) in mice. This model is used to research the pathogenic mechanisms of primary hyperoxaluria and develop related therapeutic strategies.
Application Area
Studies of glyoxylate metabolism regulation
Primary Hyperoxaluria pathogenesis and therapeutic drug evaluation
Validation Data