H11-pHsp68-Nfatc1-CreERT2
Product ID:
C001759
Background:
C57BL/6JCya
Documents:
Expressing Tissues/Cells:
Osteoclasts, cardiac endocardium, pancreas, liver, ovary, and Nfatc1-positive cells
Product Type
Age
Genotype
Sex
Quantity
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Basic Information
Model Name
H11-pHsp68-Nfatc1-CreERT2
Product ID
C001759
Gene Name
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Background
C57BL/6JCya
Gene Alias
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Classification
Cre Driver Lines
NCBI ID
--
Phenotype
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Chromosome
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More
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Document
Note: When using this mouse strain in a publication, please cite “H11-pHsp68-Nfatc1-CreERT2 mice (Catalog C001759) were purchased from Cyagen.”
Strain Description
H11-pHsp68-Nfatc1-CreERT2 mice are generated by knocking the Hsp68 minimal promoter-Kozak-CreERT2-WPRE-BGH pA-Mouse Nfatc1 enhancer cassette into the mouse H11 safe harbor locus via genome editing. Without tamoxifen treatment, CreERT2 recombinase primarily resides in the cytoplasm; nuclear translocation and recombination activity of CreERT2 only occur upon tamoxifen stimulation. When crossed with mice containing loxP sites, offspring are expected to undergo Cre-mediated recombination between loxP sites in Nfatc1-positive cells following tamoxifen administration.
Validation Data