Ntrk1-CreERT2
Product ID:
C001760
Background:
C57BL/6JCya
Documents:
Expressing Tissues/Cells:
Sensory neurons, sympathetic neurons, cholinergic neurons, paraventricular nucleus of the thalamus, bone, and Ntrk1-positive cells
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Basic Information
Model Name
Ntrk1-CreERT2
Product ID
C001760
Gene Name
Background
C57BL/6JCya
Gene Alias
Tkr; trk; TrkA
Classification
Cre Driver Lines
NCBI ID
Phenotype
Chromosome
3
Document
Note: When using this mouse strain in a publication, please cite “Ntrk1-CreERT2 mice (Catalog C001760) were purchased from Cyagen.”
Strain Description
Ntrk1-CreERT2 mice are generated by inserting an IRES-CreERT2 cassette via genome editing immediately downstream of the TAG stop codon in the mouse Ntrk1 gene. Without tamoxifen treatment, CreERT2 recombinase primarily resides in the cytoplasm; nuclear translocation and recombination activity of CreERT2 only occur upon tamoxifen stimulation. When crossed with mice containing loxP sites, offspring are expected to exhibit Cre-mediated recombination between loxP sites in Ntrk1-positive cells following tamoxifen administration.
Validation Data