Sprr1a-iCre
Product ID:
C001764
Background:
C57BL/6JCya
Documents:
Expressing Tissues/Cells:
Skin, urethra, gastric epithelium, intestine, esophagus, and Sprr1a-positive cells
Product Type
Age
Genotype
Sex
Quantity
Price:
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Basic Information
Model Name
Sprr1a-iCre
Product ID
C001764
Gene Name
Background
C57BL/6JCya
Gene Alias
SPR1a; mSPRR1A
Classification
Cre Driver Lines
NCBI ID
Phenotype
Chromosome
3
Document
Note: When using this mouse strain in a publication, please cite “Sprr1a-iCre mice (Catalog C001764) were purchased from Cyagen.”
Strain Description
Sprr1a-iCre mice are generated via genome editing by replacing the TAA stop codon of the mouse Sprr1a gene with a P2A-iCre cassette, enabling expression of iCre recombinase (codon-optimized Cre) under the control of endogenous Sprr1a regulatory elements. The expression pattern of iCre recombinase mirrors that of the endogenous Sprr1a gene. When crossed with mice containing loxP sites, Cre-mediated recombination between loxP sites is expected to occur in Sprr1a-positive cells of the offspring.
Validation Data