B6-hDMD (E49-53)
Product Type
Age
Genotype
Sex
Quantity
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Basic Information
Model Name
B6-hDMD (E49-53)
Product ID
C001775
Gene Name
Background
C57BL/6NCya
Gene Alias
BMD; CMD3B; MRX85; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Classification
Full-Gene Humanized Models,Neurological Disease Models
NCBI ID
Phenotype
Chromosome
X
Document
Note: When using this mouse strain in a publication, please cite “B6-hDMD (E49-53) mice (Catalog C001775) were purchased from Cyagen.”
Strain Description
The B6-hDMD (E49-53) mouse is a humanized model of exons 49-53 of the Dmd gene, used for researching Duchenne Muscular Dystrophy. Homozygotes are viable and fertile. In addition, based on the independently developed TurboKnockout fusion BAC recombination technology, Cyagen provides other humanized models such as [hE49-53, del E50], [hE44-45], [hE44-45, del E44], [hE44-45, c.6438+2 T to A], and [hE8-30], covering most popular research areas and offering customized services based on different mutation needs.
Application Area
Research on the pathogenesis of Duchenne Muscular Dystrophy (DMD)
Preclinical efficacy evaluation of DMD therapeutic drugs
Validation Data