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B6-hANGPTL7
Product ID:
C001789
Background:
C57BL/6JCya
Documents:
Click here to download >
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Age
Genotype
Sex
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Price:
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Basic Information
Model Name
B6-hANGPTL7
Product ID
C001789
Gene Name
ANGPTL7
Background
C57BL/6JCya
Gene Alias
AngX; CDT6; dJ647M16.1
Classification
Full-Gene Humanized Models,Ophthalmic Disease Models
NCBI ID
10218
Phenotype
MGI:3605801
Chromosome
1
More
Rare Disease Data Center >>
Document
Click here to download >>
Note
Note: When using this mouse strain in a publication, please cite “B6-hANGPTL7 mice (Catalog C001789) were purchased from Cyagen.”
Strain Description
The B6-hANGPTL7 mouse is a humanized model, constructed by replacing the sequences from 5'UTR to 3'UTR of the endogenous mouse Angptl7 gene with the corresponding human ANGPTL7 gene sequence. B6-hANGPTL7 mice can be used for research into the pathogenesis of glaucoma, type 2 diabetes mellitus (T2DM), and obstructive sleep apnea (OSA). They are also useful for the screening, development, and safety evaluation of ANGPTL7-targeted drugs.
Application Area
Area
ANGPTL7-targeted drug screening, development, and evaluation
Area
Research on the pathological mechanisms and therapeutic approaches of glaucoma
Area
Research on the pathological mechanisms and therapeutic approaches of type 2 diabetes mellitus (T2DM) and obstructive sleep apnea (OSA)
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