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B6-hIL1B
Product ID:
C001791
Background:
C57BL/6NCya
Documents:
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Strain Description
The B6-hIL1B mouse is a humanized model, constructed by replacing the coding sequences of the endogenous mouse Il1b gene with the coding sequences of the human IL1B gene. B6-hIL1B mice can be used for research into the pathogenesis of various inflammatory diseases, autoimmune diseases, cancers, and neurodegenerative diseases, as well as for the screening, development, and safety evaluation of IL1B-targeted drugs.
Application Area
Area
IL1B-targeted drug screening, development, and evaluation
Area
Research on the pathological mechanisms and therapeutic approaches of gout, rheumatoid arthritis (RA), recurrent pericarditis, type 2 diabetes (T2D), and other inflammatory and autoimmune diseases
Area
Research on the pathological mechanisms and therapeutic approaches of cancers
Area
Research on the pathological mechanisms and therapeutic approaches of neurodegenerative diseases
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