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B6-hIL23A/hIL12B/hTL1A
Product ID:
C001796
Background:
C57BL/6Cya
Documents:
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Basic Information
Model Name
B6-hIL23A/hIL12B/hTL1A
Product ID
C001796
Gene Name
IL23A, IL12B, TNFSF15
Background
C57BL/6Cya
Gene Alias
P19; SGRF; IL-23; IL-23A; IL23P19; CLMF; NKSF; CLMF2; IMD28; IMD29; NKSF2; IL-12B; TL1; TL1A; VEGI; TNLG1B; VEGI192A
Classification
Immune Target Humanized Models,Cytokine Humanized Models,Autoimmune Disease Models
NCBI ID
51561, 3593, 9966
Phenotype
MGI:1932410, MGI:96540, MGI:2180140
Chromosome
--
More
Rare Disease Data Center >>
Document
Click here to download >>
Note
Note: When using this mouse strain in a publication, please cite “B6-hIL23A/hIL12B/hTL1A mice (Catalog C001796) were purchased from Cyagen.”
Strain Description
B6-hIL23A/hIL12B/hTL1A mouse is a triple-gene humanized model for IL23A, IL12B, and TNFSF15, generated by crossing B6-hIL23A&hIL12B mice (Catalog No.: C001620) with B6-hTL1A (TNFSF15) mice (Catalog No.: C001603). This model serves as a valuable tool for researching immune-related diseases, applicable to studies on immune response regulation and autoimmune diseases. It provides a robust preclinical research platform for the screening, development, and safety evaluation of drugs targeting IL23A/IL12B/TL1A.
Application Area
Area
Screening, development, and preclinical evaluation of drugs targeting IL23A/IL12B/TL1A
Area
Research on the pathological mechanisms and therapeutic approaches of immune-related diseases
Area
Research on immune response regulation
Validation Data
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