Rpgr KO
Product Type
Age
Genotype
Sex
Quantity
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Basic Information
Model Name
Rpgr KO
Product ID
C001823
Gene Name
Background
C57BL/6JCya
Gene Alias
Rd9; Rp3h
Classification
Ophthalmic Disease Models,Rare Disease Models
NCBI ID
Phenotype
Chromosome
X
Document
Note: When using this mouse strain in a publication, please cite “Rpgr KO mice (Catalog C001823) were purchased from Cyagen.”
Strain Description
The Rpgr KO mouse is a gene knockout model created using gene-editing techniques to knock out the coding sequence of the Rpgr gene (the homolog of the human RPGR gene) in mice. This model can be used to study the pathogenic mechanisms of retinal diseases like X-linked retinitis pigmentosa (XLRP) and X-linked cone-rod dystrophy (CORDX1), providing a research basis for developing related therapeutic interventions.
Application Area
Research on X-linked retinitis pigmentosa (XLRP)
Research on X-linked cone-rod dystrophy (CORDX1)
Research on other retinal diseases
Validation Data