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B6-hPD-1/hPD-L1/hVEGFA
Product ID:
C001838
Background:
C57BL/6JCya
Documents:
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Basic Information
Model Name
B6-hPD-1/hPD-L1/hVEGFA
Product ID
C001838
Gene Name
PDCD1, CD274, VEGFA
Background
C57BL/6JCya
Gene Alias
PD1; PD-1; CD279; SLEB2; hPD-1; hPD-l; hSLE1; B7-H; B7H1; PDL1; PD-L1; hPD-L1; PDCD1L1; PDCD1LG1; VPF; VEGF; MVCD1
Classification
Tumor Target Humanized Models,Immune Target Humanized Models
NCBI ID
5133, 29126, 7422
Phenotype
MGI:104879, MGI:1926446, MGI:103178
Chromosome
--
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Rare Disease Data Center >>
Document
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Note
Note: When using this mouse strain in a publication, please cite “B6-hPD-1/hPD-L1/hVEGFA mice (Catalog C001838) were purchased from Cyagen.”
Strain Description
B6-hPD-1/hPD-L1/hVEGFA mouse is a triple-gene humanized model generated by crossing B6-hPD-1/hPD-L1 mice (Catalog No.: I001202) with B6-hVEGFA mice (Catalog No.: C001555). This model serves as a valuable tool for research on cancer immunotherapy and can also be used for the screening, development, and preclinical evaluation of PD-1/PD-L1/VEGFA-targeted drugs.
Application Area
Area
PD-1/PD-L1/VEGFA-targeted drug screening, development, and evaluation
Area
Research on the tumor development and cancer immunotherapy
Validation Data
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