B6-hELP1
Product Type
Age
Genotype
Sex
Quantity
Price:
Contact for Pricing
Basic Information
Model Name
B6-hELP1
Product ID
I001203
Gene Name
Background
C57BL/6NCya
Gene Alias
FD; DYS; IKAP; IKI3; TOT1; IKBKAP
Classification
Full-Gene Humanized Models,Neurological Disease Models
NCBI ID
Phenotype
Chromosome
9
Document
Note: When using this mouse strain in a publication, please cite “B6-hELP1 mice (Catalog I001203) were purchased from Cyagen.”
Strain Description
This strain is a mouse Elp1 gene humanized model and can be used to research Familial dysautonomia (FD). The homozygous B6-hELP1 mice are viable and fertile. In addition, based on the independently developed TurboKnockout fusion BAC recombination technology, Cyagen can also generate hot mutation (ELP1 IVS20+6T>C) models based on this strain and provide customized services for specific mutations.
Application Area
Research on the pathogenic mechanism of Familial dysautonomia (FD)
Preclinical research of ELP1-targeted drugs
Validation Data