As the popularity of our Cyagen Knockout Catalog Models repository has rapidly grown, we want to promote accessibility of these models to more researchers. To support this goal, we are now offering limited stocks of select knockout (KO) mouse models and Conditional knockout (cKO/flox) mouse models to researchers at a significant savings and with expedited delivery.
Cyagen’s Weekly Flash Sales for Knockout Models and Conditional Knockout Models will provide a list of specific gene knockout (KO) or conditional knockout (cKO) that are available until the 'off-the-shelf date' at a substantial discount. Get your ready-to-use models for as low as $1,111 per mouse - shipped in just 2 weeks!
| Eligible Products | Promotion Price |
|---|---|
| Knockout Catalog Models | $1,111/mouse |
| Conditional Knockout Catalog Models | $2,999/mouse |
Search the Flash Sale for Your Gene
| Gene Name | NCBI Gene ID | Model Type | Strain Background | Application Field | Off the Shelf Date | Order Now |
|---|---|---|---|---|---|---|
Dear Researcher,
We regret to inform you that the {[obj.data.prevKeyword]} gene you inquired about is not featured in this week's flash sale list. However, you can explore a wider selection of KO and CKO mice through the 'Cyagen Knockout Catalog Models'.Supplies of these KO/cKO mice models are limited to a first-come, first-serve basis – all inquiries must be received before the ‘off-the-shelf date’. Above price is only for heterozygous mice, homozygous mice would be 30% higher.
Check back regularly for our updated listings of KO/cKO mice available at a savings – your gene of interest could be included next!
Applications for KO Mice
Absence of gene activity can elucidate the biological roles of a gene and its potential participation in pathogenesis of human disease. Providing in vivo data on the mechanism of action (MOA) can improve the significance of your publications and even expedite results.
Data from in vitro experiments are not reliable enough on their own; in vivo data is required to validate the target for a successful drug development program.
The primary cause of drug failures is attributed to non-specificity, which may cause dangerous off-target effects. KO models can remove a functional protein target, providing an in vivo system to detect potential off-target effects of an antagonist.
