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Newsletter
Video
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| Expert Webinar: Introduction to Genetically Engineered Rodent Models |
| Jun 15, 2021 |
| View our Expert Webinar to learn about cutting-edge genome editing technologies and application limitations of animal models - such as genetically modified mice and rats. Read More > |
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Newsletter
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| Exhibiting at International Society for Stem Cell Research (ISSCR) 2021 |
| Jun 11, 2021 |
| Cyagen Biosciences is looking forward to virtually exhibiting at the International Society for Stem Cell Research (ISSCR) Annual Meeting Read More > |
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Newsletter
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| Leveraging Humanized Mice for Human Antibody Discovery |
| Jun 08, 2021 |
| With the rapid development of human antibody production, using gene editing technology to construct humanized mice with human antibodies has become an important subject in antibody drug discovery Read More > |
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Newsletter
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| Human Antibody Discovery Using In-vivo Mouse Models |
| Jun 08, 2021 |
| The continuous development and improvement of gene editing technology has driven the successful establishment of such a platform for mouse models expressing human antibody genes Read More > |
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Newsletter
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| Important Considerations in the Humanization of Antibodies |
| Jun 08, 2021 |
| The clinical application of mouse-derived antibodies has revealed some limitations, such as causing human anti-mouse antibody (HAMA) reaction, an allergic reaction that might accelerate clearance of mouse antibodies and cause anaphylaxis. Read More > |
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Newsletter
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| How Are Therapeutic Antibodies Developed? |
| Jun 08, 2021 |
| The therapeutic antibody has become a leading treatment option for cancers and other related diseases. In the past 25 years, antibody therapy has become an important treatment method for various diseases, such as cancer. Notably, from 2018 to 2019, there were about 18 new therapeutic antibody drugs approved for clinical use. Read More > |
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Newsletter
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| In Vivo Tumor Models - Cell Line-derived Tumor Xenograft (CDX) Models in Oncology Research |
| Jun 06, 2021 |
| In vivo tumor models, such as cell line-derived tumor xenograft (CDX) models, play an important role in basic research of tumorigenesis and metastasis, as well as drug development and treatment. Read More > |
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Newsletter
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| What Are Immunodeficient Mice |
| Jun 04, 2021 |
| Immunodeficient mice refer to the mice with defects in one or more immune components (such as T, B, NK cells) in the immune system. This type of mouse is widely used in the research of oncology (tumor growth, metastasis, anti-tumor drug screening), immunology (mechanisms of immune cell development and proliferation, pathology of immune diseases), infectious diseases (pathogenic mechanisms of viral/bacterial infectious diseases), and stem cell biology (human stem cell transplantation), and more. Read More > |
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Newsletter
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| Introduction to Tumor Models for Research |
| Jun 04, 2021 |
| The establishment of tumor animal models provide a powerful tool for studying the mechanism of tumorigenesis and metastasis, even validating the efficacy of anti-tumor drugs. Rodent models have many advantages in tumor research, such as fast breeding, low cost, and versatile genetic modification. These traits make them an indispensable tool for preclinical therapeutics screening. Read More > |
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Newsletter
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| How to Avoid the Risk of Residual Protein Expression in Knockout Cell Lines |
| Jun 03, 2021 |
| In this article, we review the causes of residual protein expression in knockout cell lines and provide the solution to avoid the risk of protein residue in knockout cell line models. Read More > |
