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Animal Models of Non-Alcoholic Fatty Liver Disease (NAFLD) and Steatohepatitis (NASH)
Jun 04, 2020
Non-alcoholic fatty liver disease (NAFLD), a hepatopathy syndrome affecting both adults and children, is characterized by a range of liver conditions affecting people who consume little to no alcohol, including simple fatty liver, steatohepatitis, fatty liver fibrosis, and cirrhosis. NAFLD can progress from simple fatty liver through nonalcoholic steatohepatitis (NASH) to liver fibrosis, and even lead to end-stage liver diseases, such as, liver cirrhosis, hepatocellular carcinoma (HCC), or liver failure. Read More >
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Latest Discovery
The Latest Animal Models of Chronic Pancreatitis
May 28, 2020
While chronic pancreatitis (CP) is a relatively common disease, it remains difficult to treat. This is defined as a continuous or recurrent inflammatory pancreatic disease characterized by progressive and irreversible changes in pancreatic morphology. So far, scholars around the globe have done a lot of research on the diagnosis, treatment, and pathogenesis of the disease. Read More >
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Cyagen Announces Support of Rare Genomic Institute’s BeHEARD Competition – Rare Disease Science Technology Grants Challenge
May 18, 2020
Cyagen Biosciences has committed to donate up to $83,250 of mouse model vector construction services as prizes for the Rare Genomic Institute’s BeHEARD (Helping Empower and Accelerate Research Discoveries) Challenge, which provides technology and financial grants for rare disease research. Read More >
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Latest Discovery
COVID-19
Understanding SARS-CoV-2: From the Origin to Current Research
May 13, 2020
The coronavirus disease (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become an ongoing global health emergency. Herein, we track the virus from its origin to current research efforts, with the aim of providing inspiration for further research and vaccine development. Read More >
Research Trend
COVID-19
Applications of Mouse Models for the Study of Coronavirus Diseases in Humans
May 07, 2020
The World Health Organization (WHO) announced the reclassification of the COVID-19 outbreak as a global pandemic on March 11, 2020. With the rapid spread of the disease across the globe, countries worldwide have joined the war against the SARS-CoV-2 virus. Read More >
Research Trend
Parkinson’s Disease (PD) – Researching Genetic Factors with Animal Models
Apr 29, 2020
Although most cases of Parkinson’s Disease (PD) are idiopathic, there is a small fraction of cases that have known genetic factors – presented in diagnoses of familial PD. Roughly 5% -15% of PD cases are due to a mutation occurring in one of several specific genes, commonly designated as PARK genes (due to their association with PD). Read More >
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COVID-19
Cyagen to Remain Fully Operational Throughout COVID-19
Apr 27, 2020
Despite the effects of COVID-19 on global business, we are operating at 100% proficiency - providing uninterrupted production and technical support to ensure that your research continues. We will continue serving your model generation, cloning, and virus packaging needs with the same high quality and fast turnaround as before the outbreak. Read More >
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COVID-19
Complete Collection: The Hottest Mouse Models for Coronavirus Research
Apr 10, 2020
The World Health Organization (WHO) announced the reclassification of the COVID-19 outbreak as a global pandemic on March 11, 2020. With the rapid spread of the disease across the globe, countries worldwide have joined the war against the SARS-CoV-2 virus, for which, early prevention, control, and treatment may provide valuable tools against the pandemic. Read More >
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Research Trend
Applications of Sirtuins (SIRT) Knockout Mouse Models in Disease Research
Apr 07, 2020
Sirtuins - colloquially known as the longevity genes – are a highly conserved family of NAD1+-dependent enzymes which are involved in the regulation of gene silencing, metabolism, cell division, apoptosis, and genetic material repair. Additionally, it has been reported that sirtuins play important roles in the development of multi-systemic diseases. Read More >
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Research Trend
COVID-19
Beyond Mediating Host Cell Entry of SARS-CoV-2: What Roles Does ACE2 Play?
Apr 01, 2020
In our fight against the virus and COVID-19, researchers have studied the SARS-CoV-2 virus itself and its host receptor, ACE2, from the aspects of epidemiology, pathology, virus traceability, prevention, and control measures. The human ACE2 receptor is known to interact with SARS-CoV-2 and permit its initial cell entry, making it particularly important to explore its function. Read More >