Antibody Development

Mice are one of the most commonly used model organisms in biomedical and biological research, as well as for monoclonal antibody (mAb) production. Hybridoma fusion is a widely used technology for the production of mouse monoclonal antibodies, which involves the use of physical or chemical methods to fuse antigen-activated B lymphocytes with myeloma cells to form hybridoma cells. Cyagen can provide you with reliable and high-quality antibody development services.

Service Offerings:

• Animal immunization
• Serum antibody titer testing
• Hybridoma fusion and screening
• Hybridoma sequencing
• Antibody-expressing cell line generation
• Antibody affinity testing

Deliverables:

• Immune animal serum
• Hybridoma cell culture supernatant
• Hybridoma cells
• 1-2 antibody sequences

Customer-Provided Materials:

• Antigen information
• Immunizing antigen
• Antigen for testing

Why choose Cyagen?

• Decades of experience in animal immunization
• Advanced technology for hybridoma cell preparation, enabling efficient monoclonal antibody production
• Expertise in developing high-affinity antibodies for various research applications, ensuring optimal performance in experiments and assays

Technical Route

Antibody Development using Antibody-Producing Mice

Figure 1. Process for Developing Antibodies using Antibody-Producing Mouse

Antibody Development using Human Antibody Phage Library

Figure 2. Process for Developing Antibodies using a Human Antibody Library