B6J-hCEP290 Mice


Figure 1. Fundus morphology and OCT results of C57BL/6JCya and heterozygous B6J-hCEP290 mice

The fundus morphology and retinal OCT results of heterozygous B6J-hCEP290 mice were consistent with those of C57BL/6JCya.

 

Figure 2. Electroretinogram (ERG) detection results of C57BL/6JCya and B6J-hCEP290 mice

Compared with C57BL/6JCya, the amplitudes of the a-wave and b-wave in both scotopic and photopic ERG recordings of heterozygous B6J-hCEP290 mice were nearly identical to those of the C57BL/6JCya. The retinal photoreceptor function of heterozygous B6J-hCEP290 mice were normal.