Tumor Mice and Other Hematologic System Research Models

The spontaneous tumor mouse model refers to immunocompetent mice that carry overexpression or activation mutations of oncogenes and/or the deletion or inhibitory mutation of tumor suppressor genes, either through natural mutations or artificial gene editing conditions—leading to the spontaneous formation of tumors in the body. The development process of these tumors takes place in situ within the complex tumor microenvironment. Compared to other tumor models, the molecular regulatory mechanisms and pathological mechanisms of these tumors are more similar to those occurring naturally, including the randomness of tumor development, early progression, and spontaneous tumor metastasis. This model better replicates the developmental process of human tumors and is suitable for studying the biological processes of tumor growth, evaluating immunotherapy models, and screening for anti-tumor treatment drugs in preclinical research and development.

Our Biopharmaceutical Screening and Evaluation Mouse Model Platform can provide you with multiple types of tumor mouse models and other spontaneous mouse models, such as Apc KO, etc., to support new drug development. In addition to the spontaneous and other tumor mouse models available below, we are always developing new models and open to collaborative development to advance your research—contact us for a free consultation.